Technology Process of Methyl *,S*)>-6-hydroxy-7-diphenylphosphinoyloctanoate
There total 7 articles about Methyl *,S*)>-6-hydroxy-7-diphenylphosphinoyloctanoate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium carbonate;
In
methanol;
for 3h;
Ambient temperature;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 79 percent / butyl lithium, copper(I) iodide / tetrahydrofuran
2: lithium hydroxide monohydrate / tetrahydrofuran; H2O / 15 h / Ambient temperature
3: NaBH4 / ethanol
4: 19 percent / toluene-p-sulphonic acid monohydrate / toluene / 4 h / Heating
5: 77 percent / K2CO3 / methanol / 3 h / Ambient temperature
With
lithium hydroxide; sodium tetrahydroborate; copper(l) iodide; n-butyllithium; potassium carbonate; toluene-4-sulfonic acid;
In
tetrahydrofuran; methanol; ethanol; water; toluene;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 62 percent / 1.) ozone, 2.) formic acid, hydrogen peroxide 3.) diazomethane / 1.) ozone, -70 deg C, 2.) hidrogen peroxide, formic acid, 3.) diazomethane, methanol, 0 deg C
2: lithium hydroxide monohydrate / tetrahydrofuran; H2O / 15 h / Ambient temperature
3: NaBH4 / ethanol
4: 19 percent / toluene-p-sulphonic acid monohydrate / toluene / 4 h / Heating
5: 77 percent / K2CO3 / methanol / 3 h / Ambient temperature
With
diazomethane; lithium hydroxide; sodium tetrahydroborate; formic acid; dihydrogen peroxide; potassium carbonate; toluene-4-sulfonic acid; ozone;
In
tetrahydrofuran; methanol; ethanol; water; toluene;
