4-Phenylfentanyl

Base Information

Chemical Name:4-Phenylfentanyl
CAS No.:120448-97-7
Molecular Formula:C₂₈H₃₂N₂O
Molecular Weight:412.575
Hs Code.:
UNII:L9P31JAO37
DSSTox Substance ID:DTXSID001018402
Nikkaji Number:J257.682A
Wikipedia:4-Phenylfentanyl
Wikidata:Q4637190
Metabolomics Workbench ID:152204
ChEMBL ID:CHEMBL312948

Synonyms:4-Phenylfentanyl;L9P31JAO37;N-(1-phenethyl-4-phenyl-4-piperidyl)-N-phenyl-propanamide;UNII-L9P31JAO37;120448-97-7;Propanamide, N-phenyl-N-(4-phenyl-1-(2-phenylethyl)-4-piperidinyl)-;CHEMBL312948;SCHEMBL6963035;DTXSID001018402;DB09168;PD009132;Q4637190;N-(1-Phenethyl-4-phenyl-4-piperidinyl)-N-phenylpropanamide

Suppliers and Price of 4-Phenylfentanyl

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 4-Phenylfentanyl

Chemical Property:

XLogP3:5.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:7
Exact Mass:412.251463648
Heavy Atom Count:31
Complexity:535

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCC(=O)N(C1=CC=CC=C1)C2(CCN(CC2)CCC3=CC=CC=C3)C4=CC=CC=C4

Technology Process of 4-Phenylfentanyl

There total 6 articles about 4-Phenylfentanyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3612-20-2
1-phenylmethyl-4-piperidone

: 120448-97-7
N-(1-Phenethyl-4-phenyl-piperidin-4-yl)-N-phenyl-propionamide

Guidance literature:: Multi-step reaction with 5 steps

1: p-toluenesulfonic acid / toluene / 18 h / Heating

2: cyclohexane; diethyl ether; toluene / 1) 0 deg C, 0.5 h, 2) r.t., 1.5 h

3: CHCl₃ / 360 h / Heating

4: 1) 1-chloroethyl chloroformate, 2) MeOH / 1) 1,2-dichloroethane, a) 0 deg C, 15 min, b) reflux, 2 h, 2) reflux, 4 h

5: K₂CO₃ / acetonitrile / 48 h / Heating

With methanol; carbonochloridic acid 1-chloro-ethyl ester; potassium carbonate; toluene-4-sulfonic acid; In diethyl ether; chloroform; cyclohexane; toluene; acetonitrile;
DOI:10.1021/jm00132a007

Reference yield:

: 1155-57-3
N-(1-benzylpiperidin-4-ylidene)aniline

: 120448-97-7
N-(1-Phenethyl-4-phenyl-piperidin-4-yl)-N-phenyl-propionamide

Guidance literature:: Multi-step reaction with 4 steps

1: cyclohexane; diethyl ether; toluene / 1) 0 deg C, 0.5 h, 2) r.t., 1.5 h

2: CHCl₃ / 360 h / Heating

3: 1) 1-chloroethyl chloroformate, 2) MeOH / 1) 1,2-dichloroethane, a) 0 deg C, 15 min, b) reflux, 2 h, 2) reflux, 4 h

4: K₂CO₃ / acetonitrile / 48 h / Heating

With methanol; carbonochloridic acid 1-chloro-ethyl ester; potassium carbonate; In diethyl ether; chloroform; cyclohexane; toluene; acetonitrile;
DOI:10.1021/jm00132a007

Reference yield:

: 62-53-3
aniline

: 120448-97-7
N-(1-Phenethyl-4-phenyl-piperidin-4-yl)-N-phenyl-propionamide

Guidance literature:: Multi-step reaction with 5 steps

1: p-toluenesulfonic acid / toluene / 18 h / Heating

2: cyclohexane; diethyl ether; toluene / 1) 0 deg C, 0.5 h, 2) r.t., 1.5 h

3: CHCl₃ / 360 h / Heating

4: 1) 1-chloroethyl chloroformate, 2) MeOH / 1) 1,2-dichloroethane, a) 0 deg C, 15 min, b) reflux, 2 h, 2) reflux, 4 h

5: K₂CO₃ / acetonitrile / 48 h / Heating

With methanol; carbonochloridic acid 1-chloro-ethyl ester; potassium carbonate; toluene-4-sulfonic acid; In diethyl ether; chloroform; cyclohexane; toluene; acetonitrile;
DOI:10.1021/jm00132a007