[8-(Hydroxymethyl)-7-tricyclo[4.2.2.02,5]decanyl]methanol

Base Information

• Chemical Name: [8-(Hydroxymethyl)-7-tricyclo[4.2.2.02,5]decanyl]methanol
• CAS No.: 36528-59-3
• Molecular Formula: C₁₂H₂₀O₂
• Molecular Weight: 196.29
• NSC Number: 173759
• DSSTox Substance ID: DTXSID30306042
• Mol file: 36528-59-3.mol

Synonyms:NSC173759;36528-59-3;DTXSID30306042;NSC-173759

Chemical Property of [8-(Hydroxymethyl)-7-tricyclo[4.2.2.02,5]decanyl]methanol

Chemical Property:

• Vapor Pressure: 1.86E-06mmHg at 25°C
• XLogP3: 1.9
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 196.146329876
• Heavy Atom Count: 14
• Complexity: 204

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1CC2C1C3CCC2C(C3CO)CO

Technology Process of [8-(Hydroxymethyl)-7-tricyclo[4.2.2.02,5]decanyl]methanol

There total 2 articles about [8-(Hydroxymethyl)-7-tricyclo[4.2.2.02,5]decanyl]methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

trans-7,8-Bis-(hydroxymethyl)-(anti)-tricyclo<4.2.2.02,5>-deca-3,9-dien → trans-7,8-Bis-(hydroxymethyl)-anti-tricyclo<4.2.2.02,5>decan (36528-59-3)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol;

DOI:10.1139/v72-124

Reference yield:

(1R,2R,5S,6S,7S,8S)-Tricyclo[4.2.2.02,5]deca-3,9-diene-7,8-dicarbonyl dichloride → trans-7,8-Bis-(hydroxymethyl)-anti-tricyclo<4.2.2.02,5>decan (36528-59-3)

Guidance literature:

Multi-step reaction with 2 steps

1: LiAlH₄ / diethyl ether

2: H₂ / Pd-C / methanol

With lithium aluminium tetrahydride; hydrogen; palladium on activated charcoal; In methanol; diethyl ether;

DOI:10.1139/v72-124