5-Methyl-3-(4-methylbenzene-1-sulfonyl)-2-phenylfuran

Base Information

Chemical Name:5-Methyl-3-(4-methylbenzene-1-sulfonyl)-2-phenylfuran
CAS No.:115563-21-8
Molecular Formula:C18H16O3S
Molecular Weight:312.389
Hs Code.:
DSSTox Substance ID:DTXSID60557222
Nikkaji Number:J3.402.352B
Wikidata:Q82439064
Mol file:115563-21-8.mol

Synonyms:115563-21-8;5-Methyl-2-phenyl-3-tosylfuran;5-Methyl-3-(4-methylbenzene-1-sulfonyl)-2-phenylfuran;DTXSID60557222

Suppliers and Price of 5-Methyl-3-(4-methylbenzene-1-sulfonyl)-2-phenylfuran

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-Methyl-3-(4-methylbenzene-1-sulfonyl)-2-phenylfuran

Chemical Property:

XLogP3:4.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:312.08201554
Heavy Atom Count:22
Complexity:453

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)C2=C(OC(=C2)C)C3=CC=CC=C3

Technology Process of 5-Methyl-3-(4-methylbenzene-1-sulfonyl)-2-phenylfuran

There total 7 articles about 5-Methyl-3-(4-methylbenzene-1-sulfonyl)-2-phenylfuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 1-phenyl-2-(toluene-4-sulfonyl)pent-4-yn-1-one

: 115563-21-8
5-methyl-2-phenyl-3-tosylfuran

Guidance literature:: With bismuth(lll) trifluoromethanesulfonate; In nitromethane; at 20 ℃; for 3h; Reagent/catalyst; Temperature; Solvent; Molecular sieve; Inert atmosphere;
DOI:10.1021/acs.orglett.5b00246

Reference yield: 36.0%

: 1-phenyl-2-(toluene-4-sulfonyl)pent-4-yn-1-one

: 115563-21-8
5-methyl-2-phenyl-3-tosylfuran

: 1-phenyl-2-tosyl-1,4-pentanodione

Guidance literature:: With thulium(III) trifluoromethanesulfonate; In nitromethane; water; for 20h; under 760.051 Torr; Reflux;
DOI:10.1055/s-0035-1561652

Reference yield:

: 31378-03-7
1-phenyl-2-tosylethanone

: 115563-21-8
5-methyl-2-phenyl-3-tosylfuran

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium carbonate / acetone / 0.17 h / 20 °C / Inert atmosphere

1.2: 8 h / Reflux; Inert atmosphere

2.1: bismuth(lll) trifluoromethanesulfonate / nitromethane / 3 h / 20 °C / Molecular sieve; Inert atmosphere

With bismuth(lll) trifluoromethanesulfonate; potassium carbonate; In nitromethane; acetone;
DOI:10.1021/acs.orglett.5b00246