ethyl <(1-N-5,6-di-O-benzoyl-2-deoxy-1,3-di-N-p-tolylsulfonylstreptamin-4-yl) 3,4-di-O-benzoyl-2-deoxy-2-p-tolylsulfonamido-D-threo-α-D-gluco-octo-1,5-pyranosid>uronate

Base Information

• Chemical Name: ethyl <(1-N-5,6-di-O-benzoyl-2-deoxy-1,3-di-N-p-tolylsulfonylstreptamin-4-yl) 3,4-di-O-benzoyl-2-deoxy-2-p-tolylsulfonamido-D-threo-α-D-gluco-octo-1,5-pyranosid>uronate
• CAS No.: 88897-29-4
• Molecular Formula: C₇₂H₆₉N₃O₂₁S₃
• Molecular Weight: 1408.55
• Mol file: 88897-29-4.mol

Synonyms:

Chemical Property of ethyl <(1-N-5,6-di-O-benzoyl-2-deoxy-1,3-di-N-p-tolylsulfonylstreptamin-4-yl) 3,4-di-O-benzoyl-2-deoxy-2-p-tolylsulfonamido-D-threo-α-D-gluco-octo-1,5-pyranosid>uronate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl <(1-N-5,6-di-O-benzoyl-2-deoxy-1,3-di-N-p-tolylsulfonylstreptamin-4-yl) 3,4-di-O-benzoyl-2-deoxy-2-p-tolylsulfonamido-D-threo-α-D-gluco-octo-1,5-pyranosid>uronate

There total 2 articles about ethyl <(1-N-5,6-di-O-benzoyl-2-deoxy-1,3-di-N-p-tolylsulfonylstreptamin-4-yl) 3,4-di-O-benzoyl-2-deoxy-2-p-tolylsulfonamido-D-threo-α-D-gluco-octo-1,5-pyranosid>uronate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

E-ethyl <(1-N-5,6-di-O-benzoyl-2-deoxy-1,3-di-N-p-tolylsulfonylstreptamin-4-yl) 3,4-di-O-benzoyl-2,6,7-trideoxy-2-p-tolylsulfonamido-α-D-gluco-oct-6-enopyranosid>uronate (88897-28-3) → ethyl <(1-N-5,6-di-O-benzoyl-2-deoxy-1,3-di-N-p-tolylsulfonylstreptamin-4-yl) 3,4-di-O-benzoyl-2-deoxy-2-p-tolylsulfonamido-L-threo-α-D-gluco-octo-1,5-pyranosid>uronate (88897-29-4,88929-73-1) + ethyl <(1-N-5,6-di-O-benzoyl-2-deoxy-1,3-di-N-p-tolylsulfonylstreptamin-4-yl) 3,4-di-O-benzoyl-2-deoxy-2-p-tolylsulfonamido-D-threo-α-D-gluco-octo-1,5-pyranosid>uronate (88897-29-4,88929-73-1)

Guidance literature:

With pyridine; osmium(VIII) oxide; Ambient temperature;

DOI:10.1016/0008-6215(84)85280-5

Reference yield: 66.0%

E-ethyl <(1-N-5,6-di-O-benzoyl-2-deoxy-1,3-di-N-p-tolylsulfonylstreptamin-4-yl) 3,4-di-O-benzoyl-2,6,7-trideoxy-2-p-tolylsulfonamido-α-D-gluco-oct-6-enopyranosid>uronate (88897-28-3) → ethyl <(1-N-5,6-di-O-benzoyl-2-deoxy-1,3-di-N-p-tolylsulfonylstreptamin-4-yl) 3,4-di-O-benzoyl-2-deoxy-2-p-tolylsulfonamido-L-threo-α-D-gluco-octo-1,5-pyranosid>uronate (88897-29-4,88929-73-1) + ethyl <(1-N-5,6-di-O-benzoyl-2-deoxy-1,3-di-N-p-tolylsulfonylstreptamin-4-yl) 3,4-di-O-benzoyl-2-deoxy-2-p-tolylsulfonamido-D-threo-α-D-gluco-octo-1,5-pyranosid>uronate (88897-29-4,88929-73-1)

Guidance literature:

With pyridine; osmium(VIII) oxide; Ambient temperature;

DOI:10.1016/0008-6215(84)85280-5

Reference yield:

ethyl <(1-N-5,6-di-O-benzoyl-2-deoxy-1,3-di-N-p-tolylsulfonylstreptamin-4-yl) 3,4-di-O-benzoyl-2-deoxy-2-p-tolylsulfonamido-D-threo-α-D-gluco-octo-1,5-pyranosid>uronate (88897-29-4,88929-73-1) → <(2-deoxy-1,3-di-N-p-tolylsulfonylstreptamin-4-yl) 2-deoxy-2-p-tolylsulfonamido-D-threo-α-D-gluco-octo-1,5-pyranosid>urono-8,4-lactone (88897-30-7)

Guidance literature:

With sodium methylate; In methanol; dichloromethane; for 20h; Yield given; Ambient temperature;

DOI:10.1016/0008-6215(84)85280-5

upstream raw materials:

E-ethyl <(1-N-5,6-di-O-benzoyl-2-deoxy-1,3-di-N-p-tolylsulfonylstreptamin-4-yl) 3,4-di-O-benzoyl-2,6,7-trideoxy-2-p-tolylsulfonamido-α-D-gluco-oct-6-enopyranosid>uronate

Downstream raw materials:

<(2-deoxy-1,3-di-N-p-tolylsulfonylstreptamin-4-yl) 2-deoxy-2-p-tolylsulfonamido-D-threo-α-D-gluco-octo-1,5-pyranosid>urono-8,4-lactone