(E)-3-(4-Methoxy-phenyl)-thioacrylic acid S-phenyl ester

Base Information

• Chemical Name: (E)-3-(4-Methoxy-phenyl)-thioacrylic acid S-phenyl ester
• CAS No.: 54429-67-3
• Molecular Formula: C₁₆H₁₄O₂S
• Molecular Weight: 270.352
• Mol file: 54429-67-3.mol

Synonyms:

Chemical Property of (E)-3-(4-Methoxy-phenyl)-thioacrylic acid S-phenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-3-(4-Methoxy-phenyl)-thioacrylic acid S-phenyl ester

There total 3 articles about (E)-3-(4-Methoxy-phenyl)-thioacrylic acid S-phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

[(bromodifluoromethyl)sulfanyl]benzene (78031-08-0) → (E)-3-(4-Methoxy-phenyl)-thioacrylic acid S-phenyl ester (54429-67-3)

Guidance literature:

Multi-step reaction with 2 steps

1: tris[2-phenylpyridinato-C²,N]iridium(III); 2,6-dimethylpyridine / N,N-dimethyl-formamide / 12 h / 20 °C / Inert atmosphere; Irradiation

2: silica gel

With 2,6-dimethylpyridine; tris[2-phenylpyridinato-C²,N]iridium(III); silica gel; In N,N-dimethyl-formamide;

DOI:10.1021/acs.orglett.6b01495

Reference yield:

C16H14F2OS → (E)-3-(4-Methoxy-phenyl)-thioacrylic acid S-phenyl ester (54429-67-3)

Guidance literature:

With silica gel;

DOI:10.1021/acs.orglett.6b01495

Reference yield:

→ (E)-3-(4-Methoxy-phenyl)-thioacrylic acid S-phenyl ester (54429-67-3)

Guidance literature:

4-Methoxyzimtsaeure, SOCl2, Thiophenol;

DOI:10.1515/znc-1974-9-1003

upstream raw materials:

[(bromodifluoromethyl)sulfanyl]benzene