N^α.N^ε-bis-benzyloxycarbonyl-L-lysyl azide

Base Information

• Chemical Name: N^α.N^ε-bis-benzyloxycarbonyl-L-lysyl azide
• CAS No.: 911480-68-7
• Molecular Formula: C₂₂H₂₅N₅O₅
• Molecular Weight: 439.471
• Mol file: 911480-68-7.mol

Synonyms:

Chemical Property of N^α.N^ε-bis-benzyloxycarbonyl-L-lysyl azide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N^α.N^ε-bis-benzyloxycarbonyl-L-lysyl azide

There total 2 articles about N^α.N^ε-bis-benzyloxycarbonyl-L-lysyl azide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

di-Z-L-lysine hydrazide (74283-31-1) → Nα.Nε-bis-benzyloxycarbonyl-L-lysyl azide (911480-68-7)

Guidance literature:

With hydrogenchloride; sodium nitrite; In water; acetic acid; at -10 - -5 ℃; for 0.166667h;

Reference yield:

→ Nα.Nε-bis-benzyloxycarbonyl-L-lysine amide (55592-79-5) + Nα.Nε-bis-benzyloxycarbonyl-L-lysyl azide (911480-68-7)

Guidance literature:

With hydrogenchloride; diethyl ether; acetic acid; sodium nitrite; at -3 ℃;

DOI:10.1093/oxfordjournals.rpd.a006688

Reference yield:

glycyl=>glycyl=>L-glutamic acid diethyl ester + Nα.Nε-bis-benzyloxycarbonyl-L-lysyl azide (911480-68-7) → N-{N-[N-(Nα.Nε-bis-benzyloxycarbonyl-lysyl)-glycyl]-glycyl}-glutamic acid diethyl ester

Guidance literature:

With diethyl ether; ethyl acetate; at 0 ℃; N-<N-<N-(N^α.N^ε-bis-benzyloxycarbonyl-L-lysyl)-glycyl>-glycyl>-L-glutamic acid diethyl ester;

DOI:10.1093/oxfordjournals.rpd.a006688

upstream raw materials:

di-Z-L-lysine hydrazide

Downstream raw materials:

diethyl N²,N⁶-bis((benzyloxy)carbonyl)-L-lysyl-L-aspartate

N-(N^α.N^ε-bis-benzyloxycarbonyl-L-lysyl)-L-glutamic acid diethyl ester

N^α,N^ε-di-Z-L-lysyl-glycyl-N^ε-Z-L-lysine methyl ester

(S)-6-Benzyloxycarbonylamino-2-{2-[2-((S)-2,6-bis-benzyloxycarbonylamino-hexanoylamino)-acetylamino]-acetylamino}-hexanoic acid methyl ester