1,4-Difluorocyclohexane

Base Information

• Chemical Name: 1,4-Difluorocyclohexane
• CAS No.: 116199-29-2
• Molecular Formula: C₆H₁₀F₂
• Molecular Weight: 120.142
• DSSTox Substance ID: DTXSID80412985
• Nikkaji Number: J1.194.137K,J841.247B
• Mol file: 116199-29-2.mol

Synonyms:1,4-difluorocyclohexane;116199-29-2;1,4-difluoro-cyclohexane;SCHEMBL1470777;SCHEMBL24426703;DTXSID80412985

Chemical Property of 1,4-Difluorocyclohexane

Chemical Property:

• XLogP3: 2.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 120.07505664
• Heavy Atom Count: 8
• Complexity: 54.9

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC(CCC1F)F

Technology Process of 1,4-Difluorocyclohexane

There total 1 articles about 1,4-Difluorocyclohexane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 0.5%

trans-1,4-cyclohexanediol dimethanesulfonate (37393-54-7) → trans-1-chloro-4-fluorocyclohexane (32718-98-2,55887-80-4) + trans-1,4-difluorocyclohexane (116199-29-2)

Guidance literature:

With chloride and fluoride ion bound to anion-exchange resin (AmberlystA-26); In various solvent(s); at 50 - 70 ℃; Title compound not separated from byproducts;

DOI:10.1016/S0040-4039(00)96651-6

upstream raw materials:

trans-1,4-cyclohexanediol dimethanesulfonate