2-(4-Ethylphenyl)-1,3-benzoxazol-5-amine

Base Information

Chemical Name:2-(4-Ethylphenyl)-1,3-benzoxazol-5-amine
CAS No.:116248-09-0
Molecular Formula:C15H14N2O
Molecular Weight:238.289
Hs Code.:2934999090
European Community (EC) Number:657-464-8
DSSTox Substance ID:DTXSID30352206
Nikkaji Number:J358.199C
Wikidata:Q82129222
ChEMBL ID:CHEMBL234375
Mol file:116248-09-0.mol

Synonyms:2-(4-ethylphenyl)-1,3-benzoxazol-5-amine;116248-09-0;2-(4-ethylphenyl)benzo[d]oxazol-5-amine;5-Benzoxazolamine, 2-(4-ethylphenyl)-;2-(4-Ethyl-phenyl)-benzooxazol-5-ylamine;Cambridge id 5249958;Oprea1_257740;CBDivE_014498;CHEMBL234375;SCHEMBL2242531;DTXSID30352206;BBL002657;MFCD00298091;STK105085;2-(4-ethylphenyl)-5-aminobenzoxazole;AKOS000108543;AT37193;VS-01149;BB 0245208;CS-0315263;AB00076695-01;SR-01000430160;SR-01000430160-1

Suppliers and Price of 2-(4-Ethylphenyl)-1,3-benzoxazol-5-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(4-Ethylphenyl)benzo[d]oxazol-5-amine
50mg
$ 200.00

AK Scientific
2-(4-Ethylphenyl)-1,3-benzoxazol-5-amine
500mg
$ 754.00

Total 1 raw suppliers

Chemical Property of 2-(4-Ethylphenyl)-1,3-benzoxazol-5-amine

Chemical Property:

Boiling Point:387.1±25.0 °C(Predicted)
PKA:7.02±0.10(Predicted)
PSA：52.05000
Density:1.191±0.06 g/cm3(Predicted)
LogP:4.22060
XLogP3:3.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:238.110613074
Heavy Atom Count:18
Complexity:276

Purity/Quality:: 2-(4-Ethylphenyl)benzo[d]oxazol-5-amine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1=CC=C(C=C1)C2=NC3=C(O2)C=CC(=C3)N

Technology Process of 2-(4-Ethylphenyl)-1,3-benzoxazol-5-amine

There total 2 articles about 2-(4-Ethylphenyl)-1,3-benzoxazol-5-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 619-64-7
p-ethylbenzoic acid

: 137-09-7
2,4-diaminophenol dihydrochloride

: 116248-09-0
5-amino-2-(4-ethylphenyl)-1,3-benzoxazole

Guidance literature:: With polyphosphoric acid; at 180 ℃; for 2h;
DOI:10.1007/s00044-015-1499-1

Reference yield:

: 1144108-18-8
2-(p-ethylphenyl)-5-nitrobenzoxazole

: 116248-09-0
5-amino-2-(4-ethylphenyl)-1,3-benzoxazole

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In ethanol; under 2068.65 Torr;
DOI:10.1016/j.ejmech.2008.04.001

Reference yield: 64.0%

: 527-72-0
2-thiophenylcarboxylic acid

: 116248-09-0
5-amino-2-(4-ethylphenyl)-1,3-benzoxazole

: thiophene-2-carboxylic acid [2-(4-ethyl-phenyl)-benzooxazol-5-yl]-amide

Guidance literature:: 2-thiophenylcarboxylic acid; With thionyl chloride; In benzene; at 80 ℃; for 3h;

5-amino-2-(4-ethylphenyl)-1,3-benzoxazole; With sodium hydrogencarbonate; In diethyl ether; water; at 20 ℃;
DOI:10.1002/1521-4184(200208)335:6<283::AID-ARDP283>3.0.CO;2-M