2-(4-Fluoro-phenyl)-benzooxazol-5-ylamine

Base Information

• Chemical Name: 2-(4-Fluoro-phenyl)-benzooxazol-5-ylamine
• CAS No.: 116248-10-3
• Molecular Formula: C13H9FN2O
• Molecular Weight: 228.226
• DSSTox Substance ID: DTXSID00350193
• Nikkaji Number: J358.201I
• Wikidata: Q82126004
• ChEMBL ID: CHEMBL231682
• Mol file: 116248-10-3.mol

Synonyms:116248-10-3;2-(4-Fluoro-phenyl)-benzooxazol-5-ylamine;2-(4-fluorophenyl)-1,3-benzoxazol-5-amine;5-Benzoxazolamine, 2-(4-fluorophenyl)-;2-(4-fluorophenyl)benzo[d]oxazol-5-amine;Oprea1_235468;Oprea1_789133;CHEMBL231682;DTXSID00350193;CCG-18372;MFCD00579116;STK045311;2-[4-Fluorophenyl]benzoxazol-5-amine;AKOS000108423;2-(4-fluorophenyl)-5-aminobenzoxazole;AS-63670;AB00540828;BB 0245224;CS-0313309;C80004;SR-01000461599;SR-01000461599-1

Chemical Property of 2-(4-Fluoro-phenyl)-benzooxazol-5-ylamine

Chemical Property:

• XLogP3: 2.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 228.06989108
• Heavy Atom Count: 17
• Complexity: 268

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1C2=NC3=C(O2)C=CC(=C3)N)F

Technology Process of 2-(4-Fluoro-phenyl)-benzooxazol-5-ylamine

There total 5 articles about 2-(4-Fluoro-phenyl)-benzooxazol-5-ylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

4-Fluorobenzoic acid (456-22-4) + 2,4-diaminophenol dihydrochloride (137-09-7) → 2-(4-fluorophenyl)benzo[d]oxazol-5-amine (116248-10-3)

Guidance literature:

With polyphosphoric acid; at 200 ℃; for 2h;

DOI:10.1007/s00044-015-1499-1

Reference yield: 52.0%

4-Fluorobenzoic acid (456-22-4) + 2,4-diaminophenol (95-86-3) → 2-(4-fluorophenyl)benzo[d]oxazol-5-amine (116248-10-3)

Guidance literature:

With polyphosphoric acid; at 190 ℃; for 16h;

DOI:10.1021/jm200135z

Reference yield:

2-(4-fluorophenyl)-5-nitrobenzo[d]oxazole (212758-55-9) → 2-(4-fluorophenyl)benzo[d]oxazol-5-amine (116248-10-3)

Guidance literature:

With nickel(II) chloride hexahydrate; zinc; In methanol; at 60 ℃;

DOI:10.1016/j.ejmech.2008.04.001

upstream raw materials:

4-Fluorobenzoic acid

2,4-diaminophenol dihydrochloride

2-(4-fluorophenyl)-5-nitrobenzo[d]oxazole

2,4-diaminophenol

Downstream raw materials:

N-(2-(4-fluorophenyl)benzo[d]oxazol-5-yl)benzamide

4-fluoro-N-[2-(4-fluoro-phenyl)-benzooxazol-5-yl]-benzamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 116248-10-3 5-Benzoxazolamine, 2-(4-fluorophenyl)-

Send

Send

Metric Ton KG G Pound L ML

Send

Send