(4-Benzyloxy)pyruvic Acid

Base Information

• Chemical Name: (4-Benzyloxy)pyruvic Acid
• CAS No.: 128437-99-0
• Molecular Formula: C₁₆H₁₄O₄
• Molecular Weight: 270.285
• Mol file: 128437-99-0.mol

Synonyms:

Chemical Property of (4-Benzyloxy)pyruvic Acid

Chemical Property:

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4-Benzyloxy)pyruvic Acid

There total 6 articles about (4-Benzyloxy)pyruvic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

4-<4-(Benzyloxy)benzylidene>-2-phenyloxazol-5(4H)-one (128944-41-2) → (4-Benzyloxy)pyruvic Acid (128437-99-0)

Guidance literature:

With sodium hydroxide; for 2h; Heating;

DOI:10.1002/hlca.19900730222

Reference yield: 45.0%

→ (4-Benzyloxy)pyruvic Acid (128437-99-0)

Guidance literature:

Reference yield:

p-benzyloxybenzaldehyde (4397-53-9) → (4-Benzyloxy)pyruvic Acid (128437-99-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 63.3 percent / NaOAc, Ac₂O / 1.5 h / 95 °C

2: 66 percent / 20percent aq. NaOH / 2 h / Heating

With sodium hydroxide; sodium acetate; acetic anhydride;

DOI:10.1002/hlca.19900730222

upstream raw materials:

(4-benzyloxy-phenyl)-pyruvic acid methyl ester

4-<4-(Benzyloxy)benzylidene>-2-phenyloxazol-5(4H)-one

p-benzyloxybenzaldehyde

4-hydroxyphenylpiruvic acid

Downstream raw materials:

7-(Benzyloxy)-1-<4-(benzyloxy)benzyl>-1,2,3,4-tetrahydro-6-hydroxyisoquinoline-1-carboxylic Acid