rac-9-hydroxyisoborneol

Base Information

• Chemical Name: rac-9-hydroxyisoborneol
• CAS No.: 10334-10-8
• Molecular Formula: C₁₀H₁₈O₂
• Molecular Weight: 170.252
• Mol file: 10334-10-8.mol

Synonyms:

Chemical Property of rac-9-hydroxyisoborneol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of rac-9-hydroxyisoborneol

There total 14 articles about rac-9-hydroxyisoborneol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-bromo-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one (76-29-9,1925-58-2,10293-06-8,27799-07-1,55057-87-9,64474-54-0,67337-12-6,107870-25-7) → rac-9-hydroxyisoborneol (10334-10-8,13429-50-0,20389-42-8,54831-21-9,60966-77-0,85610-81-7,107870-77-9,107870-78-0,128898-66-8,135417-24-2)

Guidance literature:

Multi-step reaction with 4 steps

1: Br₂, ClSO₃H

2: Zn, HBr

3: acetic acid / 30 h / 180 °C

4: LiAlH₄ / tetrahydrofuran / 16 h / Heating

With chlorosulfonic acid; lithium aluminium tetrahydride; hydrogen bromide; bromine; zinc; In tetrahydrofuran; acetic acid;

DOI:10.1002/jlac.198719870105

Reference yield:

rac-9-bromocamphor (2111-66-2,3751-96-0,10293-09-1,52554-78-6,60966-83-8,64474-56-2,67921-15-7,76231-54-4) → rac-9-hydroxyisoborneol (10334-10-8,13429-50-0,20389-42-8,54831-21-9,60966-77-0,85610-81-7,107870-77-9,107870-78-0,128898-66-8,135417-24-2)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic acid / 30 h / 180 °C

2: LiAlH₄ / tetrahydrofuran / 16 h / Heating

With lithium aluminium tetrahydride; In tetrahydrofuran; acetic acid;

DOI:10.1002/jlac.198719870105

Reference yield:

rac-3,9-dibromocamphor (10293-10-4,20624-59-3,60045-89-8,64474-55-1,85719-15-9,111058-98-1) → rac-9-hydroxyisoborneol (10334-10-8,13429-50-0,20389-42-8,54831-21-9,60966-77-0,85610-81-7,107870-77-9,107870-78-0,128898-66-8,135417-24-2)

Guidance literature:

Multi-step reaction with 3 steps

1: Zn, HBr

2: acetic acid / 30 h / 180 °C

3: LiAlH₄ / tetrahydrofuran / 16 h / Heating

With lithium aluminium tetrahydride; hydrogen bromide; zinc; In tetrahydrofuran; acetic acid;

DOI:10.1002/jlac.198719870105

upstream raw materials:

(-)-8-(isobutyryloxy)isobornyl isobutyrate

rac-9-acetoxycamphor

3-bromo-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one

rac-9-bromocamphor

Downstream raw materials:

C₂₃H₂₅NO₃