Technology Process of (5E,7E)-5,7-nonadienyl 3,5-dinitrobenzoate and (5Z,7E)-5,7-nonadienyl 3,5-dinitrobenzoate
There total 6 articles about (5E,7E)-5,7-nonadienyl 3,5-dinitrobenzoate and (5Z,7E)-5,7-nonadienyl 3,5-dinitrobenzoate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 52 percent / dimethylsulfoxide / 1 h
2: 1) n-butyllithium / 1) THF, -78 deg C, 30 min, 2) a) -78 deg C, 2.5 h, b) room temperature, 3 h
3: 77 percent / disodium hydrogenphosphate, sodium amalgam / tetrahydrofuran; methanol / -20 °C
4: 42 percent / sulphur dioxide, hydroquinone / methanol / 5 h / 84 °C
5: 58 percent / triethylamine, N,N-dimethyl-4-aminopyridine / CH2Cl2 / 0.5 h / Ambient temperature
With
dmap; disodium hydrogenphosphate; sodium amalgam; n-butyllithium; sulfur dioxide; triethylamine; hydroquinone;
In
tetrahydrofuran; methanol; dichloromethane; dimethyl sulfoxide;
DOI:10.1016/S0040-4020(01)96038-7
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 37.62 g / 10-camphorsulfonic acid / CH2Cl2 / 0.5 h / 0 °C
2: 52 percent / dimethylsulfoxide / 1 h
3: 1) n-butyllithium / 1) THF, -78 deg C, 30 min, 2) a) -78 deg C, 2.5 h, b) room temperature, 3 h
4: 77 percent / disodium hydrogenphosphate, sodium amalgam / tetrahydrofuran; methanol / -20 °C
5: 42 percent / sulphur dioxide, hydroquinone / methanol / 5 h / 84 °C
6: 58 percent / triethylamine, N,N-dimethyl-4-aminopyridine / CH2Cl2 / 0.5 h / Ambient temperature
With
dmap; disodium hydrogenphosphate; sodium amalgam; n-butyllithium; (1S)-10-camphorsulfonic acid; sulfur dioxide; triethylamine; hydroquinone;
In
tetrahydrofuran; methanol; dichloromethane; dimethyl sulfoxide;
DOI:10.1016/S0040-4020(01)96038-7
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 27.65 g / 48percent aqueous hydrobromic acid / benzene / 24 h / Heating
2: 37.62 g / 10-camphorsulfonic acid / CH2Cl2 / 0.5 h / 0 °C
3: 52 percent / dimethylsulfoxide / 1 h
4: 1) n-butyllithium / 1) THF, -78 deg C, 30 min, 2) a) -78 deg C, 2.5 h, b) room temperature, 3 h
5: 77 percent / disodium hydrogenphosphate, sodium amalgam / tetrahydrofuran; methanol / -20 °C
6: 42 percent / sulphur dioxide, hydroquinone / methanol / 5 h / 84 °C
7: 58 percent / triethylamine, N,N-dimethyl-4-aminopyridine / CH2Cl2 / 0.5 h / Ambient temperature
With
dmap; disodium hydrogenphosphate; sodium amalgam; n-butyllithium; (1S)-10-camphorsulfonic acid; sulfur dioxide; hydrogen bromide; triethylamine; hydroquinone;
In
tetrahydrofuran; methanol; dichloromethane; dimethyl sulfoxide; benzene;
DOI:10.1016/S0040-4020(01)96038-7
