C₁₆⁽¹³⁾CH₂₄O

Base Information

• Chemical Name: C₁₆⁽¹³⁾CH₂₄O
• CAS No.: 99302-38-2
• Molecular Formula: C₁₇H₂₄O
• Molecular Weight: 245.366
• Mol file: 99302-38-2.mol

Synonyms:

Chemical Property of C₁₆⁽¹³⁾CH₂₄O

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₆⁽¹³⁾CH₂₄O

There total 8 articles about C₁₆⁽¹³⁾CH₂₄O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(2,6,6-trimethyl-1-cyclohexen-1-yl)-3-buten-2-one (79-77-6,14901-07-6) → C16(13)CH24O (99302-38-2)

Guidance literature:

Multi-step reaction with 5 steps

1: 1.) sodium hydride / 1.) THF, 30 min, rt; 2.) THF, 0 deg C, rt 2 h

2: 1.) diisobutylaluminium hydride; 2.) water/silicagel / 1.) hexane-pet.ether, -60 deg C, -20 deg C 1 h; 2.) hexane-pet.ether, rt 1h

3: 1.) n-butyllithium / 1.) THF-hexane, -60 deg C, -20 deg C 15 min; 2.) THF-hexane, -90 deg C, -60 deg C 30 min; 3.) THF-hexane, 10 deg C

4: diazabicyclononane / toluene / 1.5 h / Heating

5: 1.) diisobutylaluminium hydride; 2.) water/silicagel / 1.) hexane-pet.ether, -60 deg C, -20 deg C 1 h; 2.) hexane-pet.ether, rt 1h

With n-butyllithium; diazabicyclononane; water; silica gel; sodium hydride; diisobutylaluminium hydride; In toluene;

Reference yield:

(2E,4E)-3-methyl-5-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4-pentadienal (3917-41-7) → C16(13)CH24O (99302-38-2)

Guidance literature:

Multi-step reaction with 3 steps

1: 1.) n-butyllithium / 1.) THF-hexane, -60 deg C, -20 deg C 15 min; 2.) THF-hexane, -90 deg C, -60 deg C 30 min; 3.) THF-hexane, 10 deg C

2: diazabicyclononane / toluene / 1.5 h / Heating

3: 1.) diisobutylaluminium hydride; 2.) water/silicagel / 1.) hexane-pet.ether, -60 deg C, -20 deg C 1 h; 2.) hexane-pet.ether, rt 1h

With n-butyllithium; diazabicyclononane; water; silica gel; diisobutylaluminium hydride; In toluene;

Reference yield:

3-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2-propenal (53018-97-6,4951-40-0) → C16(13)CH24O (99302-38-2)

Guidance literature:

Multi-step reaction with 7 steps

1: 90 percent / diethyl ether / 1 h / Heating

2: 70 percent / manganese dioxide / hexane / Ambient temperature

3: 1.) sodium hydride / 1.) THF, 30 min, rt; 2.) THF, 0 deg C, rt 2 h

4: 1.) diisobutylaluminium hydride; 2.) water/silicagel / 1.) hexane-pet.ether, -60 deg C, -20 deg C 1 h; 2.) hexane-pet.ether, rt 1h

5: 1.) n-butyllithium / 1.) THF-hexane, -60 deg C, -20 deg C 15 min; 2.) THF-hexane, -90 deg C, -60 deg C 30 min; 3.) THF-hexane, 10 deg C

6: diazabicyclononane / toluene / 1.5 h / Heating

7: 1.) diisobutylaluminium hydride; 2.) water/silicagel / 1.) hexane-pet.ether, -60 deg C, -20 deg C 1 h; 2.) hexane-pet.ether, rt 1h

With manganese(IV) oxide; n-butyllithium; diazabicyclononane; water; silica gel; sodium hydride; diisobutylaluminium hydride; In diethyl ether; hexane; toluene;

upstream raw materials:

C₁₆⁽¹³⁾CH₂₃N

4-(2,6,6-trimethyl-1-cyclohexen-1-yl)-3-buten-2-one

(2E,4E)-3-methyl-5-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4-pentadienal

3-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2-propenal

Downstream raw materials:

C₁₉⁽¹³⁾CH₂₈O

C₁₉⁽¹³⁾CH₂₇N

C₁₇⁽¹³⁾CH₂₆O

Refernces