Technology Process of C23H26N2O2
There total 8 articles about C23H26N2O2 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C16H20N2O2;
With
sodium hydride;
In
N,N-dimethyl-formamide;
for 0.25h;
(halomethyl)benzene;
In
N,N-dimethyl-formamide;
at 0 - 20 ℃;
for 16h;
DOI:10.1016/j.bmcl.2014.04.087
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium hydride / tetrahydrofuran / 0 °C
1.2: 3 h / 20 °C
2.1: sodium tetrahydroborate / methanol / 1 h / 0 °C
3.1: sodium hydride / N,N-dimethyl-formamide / 0.25 h
3.2: 16 h / 0 - 20 °C
With
sodium tetrahydroborate; sodium hydride;
In
tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2014.04.087
- Guidance literature:
-
Multi-step reaction with 8 steps
1.1: sodium ethanolate / 2 h / 0 - 20 °C
2.1: hydrazine / ethanol / 1.5 h / 80 °C
3.1: potassium carbonate / N,N-dimethyl-formamide / 18 h / 20 °C
4.1: potassium tert-butylate / toluene / 1 h / Reflux
5.1: lithium chloride / water; dimethyl sulfoxide / 10 h / 115 °C
6.1: sodium hydride / tetrahydrofuran / 0 °C
6.2: 3 h / 20 °C
7.1: sodium tetrahydroborate / methanol / 1 h / 0 °C
8.1: sodium hydride / N,N-dimethyl-formamide / 0.25 h
8.2: 16 h / 0 - 20 °C
With
sodium tetrahydroborate; potassium tert-butylate; sodium ethanolate; sodium hydride; potassium carbonate; lithium chloride; hydrazine;
In
tetrahydrofuran; methanol; ethanol; water; dimethyl sulfoxide; N,N-dimethyl-formamide; toluene;
4.1: |Dieckmann Condensation / 5.1: |Krapcho Dealkoxycarbonylation;
DOI:10.1016/j.bmcl.2014.04.087
