Di-tert-butyl (azanediylbis(ethane-2,1-diyl))dicarbamate

Base Information Edit

Chemical Name:Di-tert-butyl (azanediylbis(ethane-2,1-diyl))dicarbamate
CAS No.:117499-16-8
Molecular Formula:C14H29N3O4
Molecular Weight:303.402
Hs Code.:2924199090
European Community (EC) Number:837-916-2
DSSTox Substance ID:DTXSID10569299
Nikkaji Number:J1.390.767F
Wikidata:Q82456422
Mol file:117499-16-8.mol

Synonyms:117499-16-8;Di-tert-butyl (azanediylbis(ethane-2,1-diyl))dicarbamate;1,7-BIS-BOC-1,4,7-TRIAZAHEPTANE;10-oxa-2,5,8-triazadodecanoic acid, 11,11-dimethyl-9-oxo-, 1,1-dimethylethyl ester;MFCD11226825;tert-butyl N-[2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethylamino]ethyl]carbamate;tert-butyl N-{2-[(2-{[(tert-butoxy)carbonyl]amino}ethyl)amino]ethyl}carbamate;n,n-bis(2-(tert-butoxycarbonylamino)ethyl)amine;N,N-Bis[2-(tert-butoxycarbonylamino)ethyl]amine;bis(2-tert-butoxycarbonylaminoethyl)amine;SCHEMBL631719;DTXSID10569299;KNORWRWRHNHJAV-UHFFFAOYSA-N;AKOS016008163;AM85003;CS-W018615;HY-W017829;BP-22321;DS-18043;SY069066;EN300-266667;F11917;di-tert-butyl [iminobis(2,1-ethanediyl)]biscarbamate;N1-Boc-N2-[2-(Boc-amino)ethyl]-1,2-ethanediamine;Di-tert-butyl(azanediylbis(ethane-2,1-diyl))dicarbamate;Di-tert-butyl [azanediyldi(ethane-2,1-diyl)]biscarbamate;Di-tert-butyl (azanediylbis(ethane-2 pound not1-diyl))dicarbamate;[2-(2-tert-Butoxycarbonylamino-ethylamino)-ethyl]-carbamic acid tert-butyl ester

Suppliers and Price of Di-tert-butyl (azanediylbis(ethane-2,1-diyl))dicarbamate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
1,7-Bis-Boc-1,4,7-triazaheptane
250mg
$ 408.00

TRC
N,N-Bis[2-(tert-butoxycarbonylamino)ethyl]amine
5g
$ 1190.00

TRC
N,N-Bis[2-(tert-butoxycarbonylamino)ethyl]amine
500mg
$ 150.00

SynQuest Laboratories
1,7-Bis-Boc-1,4,7-triazaheptane
1 g
$ 461.00

Matrix Scientific
Di-tert-butyl (azanediylbis(ethane-2,1-diyl))dicarbamate 95+%
1g
$ 215.00

Iris Biotech GmbH
1,7-Bis-Boc-1,4,7-triazaheptane
5 g
$ 810.00

Iris Biotech GmbH
1,7-Bis-Boc-1,4,7-triazaheptane
1 g
$ 202.50

Frontier Specialty Chemicals
1,7-Bis-Boc-1,4,7-triazaheptane 97%
250mg
$ 454.00

Frontier Specialty Chemicals
1,7-Bis-Boc-1,4,7-triazaheptane 97%
100mg
$ 306.00

Crysdot
Di-tert-butyl(azanediylbis(ethane-2,1-diyl))dicarbamate 97%
25g
$ 1068.00

Total 21 raw suppliers

Chemical Property of Di-tert-butyl (azanediylbis(ethane-2,1-diyl))dicarbamate Edit

Chemical Property:

Melting Point:68-70°C
Boiling Point:440.5±30.0 °C(Predicted)
PKA:12.28±0.46(Predicted)
PSA：88.69000
Density:1.035±0.06 g/cm3(Predicted)
LogP:2.79810
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
Solubility.:Chloroform (Slightly), Ethyl Acetate (Slightly)
XLogP3:1.2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:10
Exact Mass:303.21580641
Heavy Atom Count:21
Complexity:300

Purity/Quality:

97% ^*data from raw suppliers

1,7-Bis-Boc-1,4,7-triazaheptane ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NCCNCCNC(=O)OC(C)(C)C
Description 1,7-BIS-BOC-1,4,7-TRIAZAHEPTANE contains two Boc protecting groups which can be removed under acidic conditions. The remaining free amines can further react with carbonyl moieties.
Uses 1,7-BIS-BOC-1,4,7-TRIAZAHEPTANE is used in the preparation of bifunctional chelators that have been then applied to the synthesis of monoclonal antibody conjugates for tumor targeting.

Technology Process of Di-tert-butyl (azanediylbis(ethane-2,1-diyl))dicarbamate

There total 14 articles about Di-tert-butyl (azanediylbis(ethane-2,1-diyl))dicarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%