1,3-Dioxane-4,6-dione, 5-[(2,5-dimethoxyphenyl)methylene]-2,2-dimethyl-

Base Information

• Chemical Name: 1,3-Dioxane-4,6-dione, 5-[(2,5-dimethoxyphenyl)methylene]-2,2-dimethyl-
• CAS No.: 117646-10-3
• Molecular Formula: C15H16O6
• Molecular Weight: 292.288
• Mol file: 117646-10-3.mol

Synonyms:5-(2,5-dimethoxybenzylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione;5-(2,5-Dimethoxy-benzylidene)-2,2-dimethyl-[1,3]dioxane-4,6-dione;5-(2,5-dimethoxybenzylidene)-2,2-dimethyl-[1,3]dioxane-4,6-dione;

Chemical Property of 1,3-Dioxane-4,6-dione, 5-[(2,5-dimethoxyphenyl)methylene]-2,2-dimethyl-

Chemical Property:

• PSA: 71.06000
• LogP: 1.92330

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,3-Dioxane-4,6-dione, 5-[(2,5-dimethoxyphenyl)methylene]-2,2-dimethyl-

There total 2 articles about 1,3-Dioxane-4,6-dione, 5-[(2,5-dimethoxyphenyl)methylene]-2,2-dimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

cycl-isopropylidene malonate (2033-24-1) + 2,5-dimethoxybenzaldehyde (93-02-7) → 5-(2',5'-dimethoxybenzylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione (117646-10-3)

Guidance literature:

In N,N-dimethyl-formamide; for 12h; Ambient temperature;

Reference yield: 35.0%

2-oxoindole (59-48-3) + cycl-isopropylidene malonate (2033-24-1) + 2,5-dimethoxybenzaldehyde (93-02-7) → 5-(2',5'-dimethoxybenzylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione (117646-10-3) + 2-[(2',3'-dihydro-2'-oxo-1H-indol-3'-yl)(2,5-dimethoxyphenyl)methyl]malonic acid

Guidance literature:

cycl-isopropylidene malonate; 2,5-dimethoxybenzaldehyde; In acetonitrile; at 20 ℃; for 0.166667h;

2-oxoindole; With rac-Pro-OH; In acetonitrile; at 20 ℃; for 50h;

DOI:10.1002/1099-0690(200210)2002:20<3481::AID-EJOC3481>3.0.CO;2-C

Reference yield: 92.0%

5-(2',5'-dimethoxybenzylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione (117646-10-3) → 5-(2,5-dimethoxybenzyl)-2,2-dimethyl-1,3-dioxane-4,6-dione (848610-51-5)

Guidance literature:

With sodium tetrahydroborate; In methanol;

DOI:10.1007/s10593-011-0690-7

upstream raw materials:

cycl-isopropylidene malonate

2,5-dimethoxybenzaldehyde

2-oxoindole

Downstream raw materials:

6-methoxycoumarin-3-carboxylic acid

3-(2',5'-dimethoxyphenyl)propanal

C₁₈H₂₀O₅

C₁₇H₁₆O₆