N-(methanesulfonyl)-16--ω-tetranor-PGE₂-carboxamide

Base Information

Chemical Name:N-(methanesulfonyl)-16--ω-tetranor-PGE₂-carboxamide
CAS No.:79124-64-4
Molecular Formula:C₂₄H₃₀F₃NO₇S
Molecular Weight:533.566
Hs Code.:

N-(methanesulfonyl)-16-<m-(trifluoromethyl)phenoxy>-ω-tetranor-PGE<sub>2</sub>-carboxamide

Synonyms:

Suppliers and Price of N-(methanesulfonyl)-16--ω-tetranor-PGE₂-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(methanesulfonyl)-16--ω-tetranor-PGE₂-carboxamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-(methanesulfonyl)-16--ω-tetranor-PGE₂-carboxamide

There total 8 articles about N-(methanesulfonyl)-16--ω-tetranor-PGE₂-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 53872-60-9
(3aR,4R,5R,6aS)-5-hydroxy-4-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-en-1-yl]-hexahydro-2H-cyclopenta[b]furan-2-one

: 79124-64-4
N-(methanesulfonyl)-16--ω-tetranor-PGE₂-carboxamide

Guidance literature:: Multi-step reaction with 5 steps

1: p-toluenesulfonic acid / CH₂Cl₂ / 0.5 h

2: diisobutylaluminum hydride / toluene; hexane / 0.33 h

3: 1.) sodium methylsulfinylcarbanide / 1.) Me₂SO, 2.) Me₂SO, 2 h

4: Jones reagent / acetone / 0.08 h / -20 °C

5: 65percent aq. acetic acid / 14 h / Ambient temperature

With jones reagent; sodium methylsulfinylcarbanide; diisobutylaluminium hydride; toluene-4-sulfonic acid; acetic acid; In hexane; dichloromethane; acetone; toluene;
DOI:10.1021/jm00143a018

Reference yield:

: 208252-64-6
(3aR,4R,5R,6aS)-5-((tetrahydro-2H-pyran-2-yl)oxy)-4-((3R,E)-3-((tetrahydro-2H-pyran-2-yl)oxy)-4-(3-(trifluoromethyl)phenoxy)but-1-en-1-yl)hexahydro-2H-cyclopenta[b]furan-2-ol

: 79124-64-4
N-(methanesulfonyl)-16--ω-tetranor-PGE₂-carboxamide

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) sodium methylsulfinylcarbanide / 1.) Me₂SO, 2.) Me₂SO, 2 h

2: Jones reagent / acetone / 0.08 h / -20 °C

3: 65percent aq. acetic acid / 14 h / Ambient temperature

With jones reagent; sodium methylsulfinylcarbanide; acetic acid; In acetone;
DOI:10.1021/jm00143a018

Reference yield:

: 54142-64-2,40695-33-8,122921-57-7
[1,1'-biphenyl]-4-carboxylic acid (3aR,4R,5R,6aS)-hexahydro-2-oxo-4-[(1E)-3-oxo-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]-2H-cyclopenta[b]furan-5-yl ester

: 79124-64-4
N-(methanesulfonyl)-16--ω-tetranor-PGE₂-carboxamide

Guidance literature:: Multi-step reaction with 7 steps

1: lithium triethylborohydride / tetrahydrofuran / 0.5 h

2: potassium carbonate / methanol; tetrahydrofuran / 2.5 h

3: p-toluenesulfonic acid / CH₂Cl₂ / 0.5 h

4: diisobutylaluminum hydride / toluene; hexane / 0.33 h

5: 1.) sodium methylsulfinylcarbanide / 1.) Me₂SO, 2.) Me₂SO, 2 h

6: Jones reagent / acetone / 0.08 h / -20 °C

7: 65percent aq. acetic acid / 14 h / Ambient temperature

With jones reagent; sodium methylsulfinylcarbanide; diisobutylaluminium hydride; lithium triethylborohydride; potassium carbonate; toluene-4-sulfonic acid; acetic acid; In tetrahydrofuran; methanol; hexane; dichloromethane; acetone; toluene;
DOI:10.1021/jm00143a018