N-(3-phenylpropyl)benzenesulfonamide

Base Information

• Chemical Name: N-(3-phenylpropyl)benzenesulfonamide
• CAS No.: 117824-61-0
• Molecular Formula: C15H17NO2S
• Molecular Weight: 275.371
• Mol file: 117824-61-0.mol

Synonyms:

Chemical Property of N-(3-phenylpropyl)benzenesulfonamide

Chemical Property:

• PSA: 54.55000
• LogP: 4.06940

Purity/Quality:

N-(3-PHENYLPROPYL)BENZENESULFONAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-(3-phenylpropyl)benzenesulfonamide

There total 2 articles about N-(3-phenylpropyl)benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.7%

N-(3-Phenyl-propionyl)-benzenesulfonamide (104937-92-0) → N-(3-Phenylpropyl)benzenesulfonamide (117824-61-0)

Guidance literature:

With dimethylsulfide borane complex; In tetrahydrofuran; for 70h; Ambient temperature;

Reference yield:

benzenesulfonamide (98-10-2) + 3-Phenyl-1-propanol (122-97-4) → N-(3-Phenylpropyl)benzenesulfonamide (117824-61-0)

Guidance literature:

With iridium(III) chloride; potassium carbonate; at 150 ℃; for 24h;

DOI:10.1021/jo200862p

Reference yield: 100.0%

N-(3-Phenylpropyl)benzenesulfonamide (117824-61-0) → benzenesulfonamide (98-10-2)

Guidance literature:

With 4,4’-bis(diacetoxyiodo)biphenyl; iodine; In 1,2-dichloro-ethane; at 30 - 40 ℃; for 3h; sonication;

DOI:10.1016/j.tet.2006.09.112

upstream raw materials:

N-(3-Phenyl-propionyl)-benzenesulfonamide

benzenesulfonamide

3-Phenyl-1-propanol

Downstream raw materials:

3-Phenylpropan-1-amine

1-((4-nitrophenyl)sulfonyl)-1,2,3,4-tetrahydroquinoline

3-phenyl-propionaldehyde

benzenesulfonamide

Refernces

• 1、 Belletire, J. L.,Fry, D. F.. "A USEFUL APPROACH TO PRIMARY AMINES". . p. 29 - 36. Retrieved 2007/10/02.