FUB 360

Base Information

• Chemical Name: FUB 360
• CAS No.: 184025-60-3
• Molecular Formula: C₁₆H₂₀N₂O₂
• Molecular Weight: 272.347
• Mol file: 184025-60-3.mol

Synonyms:

Chemical Property of FUB 360

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of FUB 360

There total 6 articles about FUB 360 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-(1-trityl-1H-imidazol-4-yl)propan-1-ol (152030-49-4) → FUB 360 (184025-60-3)

Guidance literature:

Multi-step reaction with 3 steps

1.1: NaH / toluene

1.2: toluene / Heating

2.1: LiAlH₄ / tetrahydrofuran; diethyl ether / Heating

3.1: aq. HCl / tetrahydrofuran / Heating

With hydrogenchloride; lithium aluminium tetrahydride; sodium hydride; In tetrahydrofuran; diethyl ether; toluene; 1.1: Metallation / 1.2: Etherification / 2.1: Reduction / 3.1: detritylation;

DOI:10.1016/S0960-894X(00)00473-X

Reference yield:

cyclopropyl-{4-[3-(1-trityl-1H-imidazol-4-yl)-propoxy]-phenyl}-methanol → FUB 360 (184025-60-3)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; Heating;

DOI:10.1016/S0960-894X(00)00473-X

Reference yield:

cyclopropyl 4-hydroxyphenyl ketone (36116-18-4) → FUB 360 (184025-60-3)

Guidance literature:

Multi-step reaction with 3 steps

1: Ph₃P; DEAD / tetrahydrofuran

2: LiAlH₄ / tetrahydrofuran; diethyl ether / Heating

3: aq. HCl / tetrahydrofuran / Heating

With hydrogenchloride; lithium aluminium tetrahydride; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; diethyl ether; 1: Mitsunobu reaction / 2: Reduction / 3: detritylation;

DOI:10.1016/S0960-894X(00)00473-X

upstream raw materials:

cyclopropyl(4-fluorophenyl)methanone

cyclopropyl 4-hydroxyphenyl ketone

3-(1-trityl-1H-imidazol-4-yl)propan-1-ol

cyclopropyl-{4-[3-(1-trityl-1H-imidazol-4-yl)-propoxy]-phenyl}-methanone