Technology Process of C23H24F2N6O4
There total 8 articles about C23H24F2N6O4 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / 1,2-dimethoxyethane; water / 100 °C / Inert atmosphere
2.1: N,N-dimethyl-formamide; trichlorophosphate / 1,2-dichloro-ethane / 3 h / 80 °C
3.1: potassium hexamethylsilazane / tetrahydrofuran / 1 h / 0 °C
3.2: 24 h / 0 - 20 °C
4.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 5 °C / Inert atmosphere
4.2: 5 - 80 °C
With
tetrakis(triphenylphosphine) palladium(0); potassium hexamethylsilazane; sodium hydride; sodium carbonate; N,N-dimethyl-formamide; trichlorophosphate;
In
tetrahydrofuran; 1,2-dimethoxyethane; water; 1,2-dichloro-ethane; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: hydrogen bromide; acetic acid / 3 h / 40 - 50 °C
2.1: N,N-dimethyl-formamide; trichlorophosphate / 1,2-dichloro-ethane / 3 h / 80 °C
3.1: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / 1,2-dimethoxyethane; water / 2 h / Inert atmosphere; Reflux
4.1: potassium hexamethylsilazane / tetrahydrofuran / 1 h / 0 °C
4.2: 24 h / 0 - 20 °C
5.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 5 °C / Inert atmosphere
5.2: 5 - 80 °C
With
tetrakis(triphenylphosphine) palladium(0); hydrogen bromide; potassium hexamethylsilazane; sodium hydride; sodium carbonate; acetic acid; N,N-dimethyl-formamide; trichlorophosphate;
In
tetrahydrofuran; 1,2-dimethoxyethane; water; 1,2-dichloro-ethane; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: N,N-dimethyl-formamide; trichlorophosphate / 1,2-dichloro-ethane / 3 h / 80 °C
2.1: potassium hexamethylsilazane / tetrahydrofuran / 1 h / 0 °C
2.2: 24 h / 0 - 20 °C
3.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 5 °C / Inert atmosphere
3.2: 5 - 80 °C
With
potassium hexamethylsilazane; sodium hydride; N,N-dimethyl-formamide; trichlorophosphate;
In
tetrahydrofuran; 1,2-dichloro-ethane; N,N-dimethyl-formamide;