o-propiophenone

Base Information

• Chemical Name: o-propiophenone
• CAS No.: 78388-05-3
• Molecular Formula: C₁₇H₁₆O₅
• Molecular Weight: 300.311
• Mol file: 78388-05-3.mol

Synonyms:

Chemical Property of o-propiophenone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of o-propiophenone

There total 1 articles about o-propiophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(2-Hydroxy-phenyl)-propan-1-on (610-99-1) + 4-methoxyphenylchloroformate (7693-41-6) → o-propiophenone (78388-05-3)

Guidance literature:

DOI:10.1039/c39810000282

Reference yield:

o-propiophenone (78388-05-3) → 2-(4-Methoxy-phenoxy)-3-methyl-chromen-4-one

Guidance literature:

Multi-step reaction with 2 steps

1: 1) CuBr₂ / 1) AcOEt, CHCl₃, reflux, 2) CHCl₃, reflux

2: N,N-diisopropylethylamine / toluene / 2 h / Heating

With N-ethyl-N,N-diisopropylamine; copper(ll) bromide; In toluene;

DOI:10.1039/c39810000282

Reference yield:

triphenylphosphine (603-35-0) + o-propiophenone (78388-05-3) → {2-[2-(4-Methoxy-phenoxycarbonyloxy)-phenyl]-1-methyl-2-oxo-ethyl}-triphenyl-phosphonium; bromide

Guidance literature:

With copper(ll) bromide; Multistep reaction; 1) AcOEt, CHCl₃, reflux, 2) CHCl₃, reflux;

DOI:10.1039/c39810000282

upstream raw materials:

1-(2-Hydroxy-phenyl)-propan-1-on

4-methoxyphenylchloroformate