Technology Process of C20H19NO3
There total 4 articles about C20H19NO3 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C12H13NO2;
With
potassium hexamethylsilazane;
In
tetrahydrofuran;
at -78 ℃;
With
chlorophosphoric acid diphenyl ester;
In
tetrahydrofuran;
at -78 ℃;
for 0.333333h;
(2-formyl-5-methoxyphenyl)boronic acid;
Further stages;
DOI:10.1016/j.tetlet.2011.01.113
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: oxalyl dichloride; N,N-dimethyl-formamide / toluene / 2 h / 20 °C
2.1: triethylamine / dichloromethane / 4 h / 20 °C
3.1: sodium hydride / tetrahydrofuran / 2 h / 20 °C
3.2: 5 h / -78 - 20 °C
4.1: potassium hexamethylsilazane / tetrahydrofuran / -78 °C
4.2: 0.33 h / -78 °C
With
oxalyl dichloride; potassium hexamethylsilazane; sodium hydride; triethylamine; N,N-dimethyl-formamide;
In
tetrahydrofuran; dichloromethane; toluene;
4.1: Suzuki-Miyaura cross-coupling / 4.2: Suzuki-Miyaura cross-coupling;
DOI:10.1016/j.tetlet.2011.01.113
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sodium hydride / tetrahydrofuran / 2 h / 20 °C
1.2: 5 h / -78 - 20 °C
2.1: potassium hexamethylsilazane / tetrahydrofuran / -78 °C
2.2: 0.33 h / -78 °C
With
potassium hexamethylsilazane; sodium hydride;
In
tetrahydrofuran;
2.1: Suzuki-Miyaura cross-coupling / 2.2: Suzuki-Miyaura cross-coupling;
DOI:10.1016/j.tetlet.2011.01.113
