Technology Process of C19H18N4O6
There total 8 articles about C19H18N4O6 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetrabutyl ammonium fluoride; acetic acid;
In
tetrahydrofuran;
at 20 ℃;
for 0.5h;
DOI:10.1021/jo300230z
- Guidance literature:
-
Multi-step reaction with 8 steps
1: sodium hydroxide / N,N-dimethyl-formamide / 70 °C
2: pyridine / dichloromethane / 20 °C
3: trifluoroacetic acid / 0.17 h / 20 °C
4: N-iodo-succinimide / N,N-dimethyl-formamide / 1 h / 20 °C
5: water; methylamine / methanol / 20 °C
6: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran / 1 h / 0 - 20 °C
7: triphenyl-arsane; palladium diacetate; silver carbonate / chloroform / Reflux
8: tetrabutyl ammonium fluoride; acetic acid / tetrahydrofuran / 0.5 h / 20 °C
With
pyridine; N-iodo-succinimide; triphenyl-arsane; tetrabutyl ammonium fluoride; water; palladium diacetate; acetic acid; triphenylphosphine; silver carbonate; methylamine; trifluoroacetic acid; sodium hydroxide; diethylazodicarboxylate;
In
tetrahydrofuran; methanol; dichloromethane; chloroform; N,N-dimethyl-formamide;
6: Mitsunobu reaction / 7: Heck coupling;
DOI:10.1021/jo300230z
- Guidance literature:
-
Multi-step reaction with 5 steps
1: N-iodo-succinimide / N,N-dimethyl-formamide / 1 h / 20 °C
2: water; methylamine / methanol / 20 °C
3: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran / 1 h / 0 - 20 °C
4: triphenyl-arsane; palladium diacetate; silver carbonate / chloroform / Reflux
5: tetrabutyl ammonium fluoride; acetic acid / tetrahydrofuran / 0.5 h / 20 °C
With
N-iodo-succinimide; triphenyl-arsane; tetrabutyl ammonium fluoride; water; palladium diacetate; acetic acid; triphenylphosphine; silver carbonate; methylamine; diethylazodicarboxylate;
In
tetrahydrofuran; methanol; chloroform; N,N-dimethyl-formamide;
3: Mitsunobu reaction / 4: Heck coupling;
DOI:10.1021/jo300230z