[4-Methyl-2-(1-pyrrolidinyl)-3-thienyl]phenylmethanone

Base Information

Chemical Name:[4-Methyl-2-(1-pyrrolidinyl)-3-thienyl]phenylmethanone
CAS No.:86662-25-1
Molecular Formula:C₁₆H₁₇NOS
Molecular Weight:271.383
Hs Code.:
DSSTox Substance ID:DTXSID001211735

Synonyms:DTXSID001211735;[4-Methyl-2-(1-pyrrolidinyl)-3-thienyl]phenylmethanone;86662-25-1

Suppliers and Price of [4-Methyl-2-(1-pyrrolidinyl)-3-thienyl]phenylmethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of [4-Methyl-2-(1-pyrrolidinyl)-3-thienyl]phenylmethanone

Chemical Property:

XLogP3:4.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:271.10308534
Heavy Atom Count:19
Complexity:321

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CSC(=C1C(=O)C2=CC=CC=C2)N3CCCC3

Technology Process of [4-Methyl-2-(1-pyrrolidinyl)-3-thienyl]phenylmethanone

There total 2 articles about [4-Methyl-2-(1-pyrrolidinyl)-3-thienyl]phenylmethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 86662-38-6
(E)-1-Phenyl-3-prop-2-ynylsulfanyl-3-pyrrolidin-1-yl-propenone

: 86662-25-1
3-Benzoyl-2-(N-pyrrolidino)-4-methylthiophene

Guidance literature:: In benzene; at 70 - 80 ℃; for 7h; Yield given;
DOI:10.1055/s-1983-30359

Reference yield:

: 53354-70-4
(2-Benzoyl-thioessigsaeure)pyrrolidid

: 86662-25-1
3-Benzoyl-2-(N-pyrrolidino)-4-methylthiophene

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) K₂CO₃ / 1.) acetone, reflux, 2.5 h; 2.) room temp., 3 h

2: benzene / 7 h / 70 - 80 °C

With potassium carbonate; In benzene;
DOI:10.1055/s-1983-30359