C₁₄H₁₈O₃

Base Information

• Chemical Name: C₁₄H₁₈O₃
• CAS No.: 1622095-30-0
• Molecular Formula: C₁₄H₁₈O₃
• Molecular Weight: 234.295
• Mol file: 1622095-30-0.mol

Synonyms:

Chemical Property of C₁₄H₁₈O₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₄H₁₈O₃

There total 11 articles about C₁₄H₁₈O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C14H20O3 (166376-61-0) → C14H18O3 (1622095-30-0)

Guidance literature:

With manganese(IV) oxide; In dichloromethane; at 20 ℃; for 20h;

DOI:10.1002/ejoc.201402096

Reference yield:

C20H19NO5 (1622095-12-8) → C14H18O3 (1622095-30-0)

Guidance literature:

Multi-step reaction with 5 steps

1.1: dichloromethane / 20 h / 20 °C

2.1: sodium hexamethyldisilazane / tetrahydrofuran / 2.5 h / -78 °C / Inert atmosphere

2.2: 11.5 h / -78 - -5 °C

3.1: sodium tetrahydroborate / tetrahydrofuran; water / 18 h / 20 °C

4.1: diisobutylaluminium hydride / dichloromethane; cyclohexane / 2 h / -78 °C / Inert atmosphere

5.1: manganese(IV) oxide / dichloromethane / 20 h / 20 °C

With manganese(IV) oxide; sodium tetrahydroborate; sodium hexamethyldisilazane; diisobutylaluminium hydride; In tetrahydrofuran; dichloromethane; cyclohexane; water; 1.1: |Wittig Olefination;

DOI:10.1002/ejoc.201402096

Reference yield:

4-(4-Formyl-phenoxy)butyric acid (99865-70-0) → C14H18O3 (1622095-30-0)

Guidance literature:

Multi-step reaction with 6 steps

1.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap / dichloromethane / 14 h / 20 °C

2.1: dichloromethane / 20 h / 20 °C

3.1: sodium hexamethyldisilazane / tetrahydrofuran / 2.5 h / -78 °C / Inert atmosphere

3.2: 11.5 h / -78 - -5 °C

4.1: sodium tetrahydroborate / tetrahydrofuran; water / 18 h / 20 °C

5.1: diisobutylaluminium hydride / dichloromethane; cyclohexane / 2 h / -78 °C / Inert atmosphere

6.1: manganese(IV) oxide / dichloromethane / 20 h / 20 °C

With dmap; manganese(IV) oxide; sodium tetrahydroborate; sodium hexamethyldisilazane; diisobutylaluminium hydride; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In tetrahydrofuran; dichloromethane; cyclohexane; water; 2.1: |Wittig Olefination;

DOI:10.1002/ejoc.201402096

upstream raw materials:

C₁₆H₂₂O₄

4-(4-Formyl-phenoxy)butyric acid

C₁₄H₂₀O₃

C₂₀H₁₉NO₅