(+)-pederine

Base Information

• Chemical Name: (+)-pederine
• CAS No.: 111212-06-7
• Molecular Formula: C₂₅H₄₅NO₉
• Molecular Weight: 503.634
• Mol file: 111212-06-7.mol

Synonyms:

Chemical Property of (+)-pederine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+)-pederine

There total 16 articles about (+)-pederine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

(+/-)-pederin dibenzoate (111194-21-9,123483-10-3) → (+/-)-pederin (27973-72-4,85249-20-3,111212-06-7)

Guidance literature:

With lithium hydroxide; In methanol; at 50 ℃; for 5h;

DOI:10.1016/S0040-4020(01)81981-5

Reference yield:

Acetic acid (S)-chlorocarbonyl-((2R,5R,6R)-2-methoxy-5,6-dimethyl-4-methylene-tetrahydro-pyran-2-yl)-methyl ester → (+)-10-epipederine (27973-72-4,85249-20-3,111212-06-7)

Guidance literature:

Multi-step reaction with 3 steps

1: Et₃N / 2 h

2: NaBH₄ / ethanol / 0.5 h / 0 °C

3: 1 N LiOH / methanol / 2 h / Ambient temperature

With lithium hydroxide; sodium tetrahydroborate; triethylamine; In methanol; ethanol;

DOI:10.1016/S0040-4039(00)88691-8

Reference yield:

Acetic acid (S)-chlorocarbonyl-((2R,5R,6R)-2-methoxy-5,6-dimethyl-4-methylene-tetrahydro-pyran-2-yl)-methyl ester → (+)-pederine (27973-72-4,85249-20-3,111212-06-7)

Guidance literature:

Multi-step reaction with 3 steps

1: Et₃N / 2 h

2: NaBH₄ / ethanol / 0.5 h / 0 °C

3: 1 N LiOH / methanol / 2 h / Ambient temperature

With lithium hydroxide; sodium tetrahydroborate; triethylamine; In methanol; ethanol;

DOI:10.1016/S0040-4039(00)88691-8

upstream raw materials:

(+/-)-pederin dibenzoate

Benzoic acid (S)-chlorocarbonyl-((2R,4S,5R,6R)-2-methoxy-5,6-dimethyl-4-phenylselanylmethyl-tetrahydro-pyran-2-yl)-methyl ester

C₄₅H₅₉NO₁₁Se

(+/-)-benzoylselenopederic acid