Benzenemethanol, 4-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-

Base Information

• Chemical Name: Benzenemethanol, 4-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-
• CAS No.: 118992-89-5
• Molecular Formula: C14H24O2Si
• Molecular Weight: 252.429
• DSSTox Substance ID: DTXSID30445127
• Nikkaji Number: J464.635E
• Mol file: 118992-89-5.mol

Synonyms:118992-89-5;Benzenemethanol, 4-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-;(4-(((tert-Butyldimethylsilyl)oxy)methyl)phenyl)methanol;[4-[[tert-butyl(dimethyl)silyl]oxymethyl]phenyl]methanol;4-(tert-butyldimethylsilyloxymethyl)benzyl alcohol;SCHEMBL3178345;DTXSID30445127;NXRUAHNSDOIJAG-UHFFFAOYSA-N;CS-0088899;1,4-PHENYLENEDIMETHANOL MONO-TBS ETHER;D74728;4-(tert-Butyldimethylsiloxymethyl)benzyl alcohol;4-(tert-butyldimethylsilyloxymethyl)benzylalcohol;A1-30648

Chemical Property of Benzenemethanol, 4-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-

Chemical Property:

• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 252.154556538
• Heavy Atom Count: 17
• Complexity: 225

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C)[Si](C)(C)OCC1=CC=C(C=C1)CO

Technology Process of Benzenemethanol, 4-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-

There total 19 articles about Benzenemethanol, 4-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-<(tert-butyldimethylsiloxy)methyl>benzoic acid (104292-83-3) → [4-({[tert-butyl(dimethyl)silyl]oxy}methyl)phenyl]methanol (118992-89-5)

Guidance literature:

With borane-THF; In tetrahydrofuran; at 0 - 20 ℃; for 6h;

Reference yield: 97.0%

1-(tert-butyldimethylsilyloxymethyl)-4-triethylsilyloxymethylbenzene → p-xylylene glycol (589-29-7) + [4-({[tert-butyl(dimethyl)silyl]oxy}methyl)phenyl]methanol (118992-89-5)

Guidance literature:

With MCM-41; In methanol; for 8h; Yields of byproduct given; Ambient temperature;

Reference yield: 96.0%

C16H26O3Si (1258782-55-6) → [4-({[tert-butyl(dimethyl)silyl]oxy}methyl)phenyl]methanol (118992-89-5)

Guidance literature:

With methanol; oxo[hexa(trifluoroacetato)]tetrazinc; for 12h; Reflux; Inert atmosphere;

DOI:10.1002/chem.201000960

upstream raw materials:

1,4-di(t-butyldimethylsiloxymethyl)benzene

4-(tert-butyldimethylsilyloxymethyl)benzoic acid methyl ester

4-<(tert-butyldimethylsiloxy)methyl><(triisopropylsiloxy)methyl>benzene

p-xylylene glycol

Downstream raw materials:

4-(bromomethyl)-t-butyldimethylsilyloxymethylbenzene

4-((tert-butyldimethylsilyloxy)methyl)benzaldehyde

N-[4-(t-butyldimethylsiloxymethyl)benzyloxy]phthalimide

4-({[Tert-butyl(dimethyl)silyl]oxy}methyl)benzyl methanesulfonate