Technology Process of 6-phenyl-N-(pyridin-3-yl)pyridin-3-amine
There total 4 articles about 6-phenyl-N-(pyridin-3-yl)pyridin-3-amine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
palladium diacetate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl;
In
toluene;
Inert atmosphere;
Reflux;
DOI:10.1021/jm400240r
- Guidance literature:
-
Multi-step reaction with 3 steps
1: sodium carbonate; tetrakis(triphenylphosphine) palladium(0) / toluene; ethanol; water / 4 h / Inert atmosphere; Reflux
2: sodium iodide; copper(l) iodide; N,N-dimethylethylenediamine / 21 h / 110 °C / Inert atmosphere
3: palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; caesium carbonate / toluene / Inert atmosphere; Reflux
With
copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); palladium diacetate; sodium carbonate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; N,N-dimethylethylenediamine; sodium iodide;
In
ethanol; water; toluene;
1: |Suzuki Coupling;
DOI:10.1021/jm400240r
- Guidance literature:
-
Multi-step reaction with 2 steps
1: sodium iodide; copper(l) iodide; N,N-dimethylethylenediamine / 21 h / 110 °C / Inert atmosphere
2: palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; caesium carbonate / toluene / Inert atmosphere; Reflux
With
copper(l) iodide; palladium diacetate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; N,N-dimethylethylenediamine; sodium iodide;
In
toluene;
DOI:10.1021/jm400240r
