Benzaldehyde, 4-amino-2,3,5,6-tetrafluoro-

Base Information

• Chemical Name: Benzaldehyde, 4-amino-2,3,5,6-tetrafluoro-
• CAS No.: 119060-58-1
• Molecular Formula: C7H3F4NO
• Molecular Weight: 193.101
• DSSTox Substance ID: DTXSID50471685
• Mol file: 119060-58-1.mol

Synonyms:4-amino-2,3,5,6-tetrafluorobenzaldehyde;119060-58-1;Benzaldehyde, 4-amino-2,3,5,6-tetrafluoro-;4-amino-2,3,5,6-tetrafluoro-benzaldehyde;SCHEMBL3065462;DTXSID50471685;AT26945;EN300-3073816

Chemical Property of Benzaldehyde, 4-amino-2,3,5,6-tetrafluoro-

Chemical Property:

• XLogP3: 1.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 1
• Exact Mass: 193.01507637
• Heavy Atom Count: 13
• Complexity: 187

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C(=O)C1=C(C(=C(C(=C1F)F)N)F)F

Technology Process of Benzaldehyde, 4-amino-2,3,5,6-tetrafluoro-

There total 5 articles about Benzaldehyde, 4-amino-2,3,5,6-tetrafluoro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

4-amino-2,3,5,6-tetrafluorobenzonitrile (17823-38-0) → 4-amino-2,3,5,6-tetrafluorobenzyl aldehyde (119060-58-1)

Guidance literature:

With diisobutylaluminium hydride; In benzene; for 10h;

DOI:10.1055/s-1988-27643

Reference yield: 73.0%

4-(hydroxymethyl)-2,3,5,6-tetrafluoroaniline (17078-34-1) → 4-amino-2,3,5,6-tetrafluorobenzyl aldehyde (119060-58-1)

Guidance literature:

With pyridinium chlorochromate; In dichloromethane; at 25 ℃;

DOI:10.1039/d0ob00936a

Reference yield:

4-azido-2,3,5,6-tetrafluorobenzaldehyde (120384-18-1) → 4-amino-2,3,5,6-tetrafluorobenzyl aldehyde (119060-58-1) + 4-Diethoxymethyl-2,3,5,6-tetrafluoro-phenylamine

Guidance literature:

With tin(ll) chloride; In ethanol; ethyl acetate; for 0.0166667h; Yield given. Yields of byproduct given; Ambient temperature;

DOI:10.1080/00397919308009788

upstream raw materials:

4-amino-2,3,5,6-tetrafluorobenzonitrile

4-azido-2,3,5,6-tetrafluorobenzaldehyde

ethyl acetate

Pentafluorobenzonitrile

Downstream raw materials:

Ethyl (E)-4-amino-2,3,5,6-tetrafluorocinnamate