Technology Process of N6-phenethylgriseolic acid
There total 5 articles about N6-phenethylgriseolic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 100 percent / sodium nitrit / acetic acid; H2O
2: 80 percent / pyridine / 3 h / Ambient temperature
3: phosphorus oxychloride, N,N-diethylaniline / ethyl acetate / 0.33 h / Heating
4: 1.) NaOH; 2.) HCl / methanol / Ambient temperature
With
pyridine; hydrogenchloride; sodium hydroxide; N,N-diethylaniline; sodium nitrite; trichlorophosphate;
In
methanol; water; acetic acid; ethyl acetate;
DOI:10.1248/cpb.36.1309
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 96 percent / acetone; H2O / 16 h / Ambient temperature
2: 100 percent / sodium nitrit / acetic acid; H2O
3: 80 percent / pyridine / 3 h / Ambient temperature
4: phosphorus oxychloride, N,N-diethylaniline / ethyl acetate / 0.33 h / Heating
5: 1.) NaOH; 2.) HCl / methanol / Ambient temperature
With
pyridine; hydrogenchloride; sodium hydroxide; N,N-diethylaniline; sodium nitrite; trichlorophosphate;
In
methanol; water; acetic acid; ethyl acetate; acetone;
DOI:10.1248/cpb.36.1309
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 80 percent / pyridine / 3 h / Ambient temperature
2: phosphorus oxychloride, N,N-diethylaniline / ethyl acetate / 0.33 h / Heating
3: 1.) NaOH; 2.) HCl / methanol / Ambient temperature
With
pyridine; hydrogenchloride; sodium hydroxide; N,N-diethylaniline; trichlorophosphate;
In
methanol; ethyl acetate;
DOI:10.1248/cpb.36.1309
