Toluene-4-sulfonate(2-{[(E)-(2S,3S)-3-(tert-butyl-diphenyl-silanyloxy)-2-octadecanoylamino-octadec-4-enyloxy]-methoxy-thiophosphoryloxy}-ethyl)-trimethyl-ammonium;

Base Information

• Chemical Name: Toluene-4-sulfonate(2-{[(E)-(2S,3S)-3-(tert-butyl-diphenyl-silanyloxy)-2-octadecanoylamino-octadec-4-enyloxy]-methoxy-thiophosphoryloxy}-ethyl)-trimethyl-ammonium
• CAS No.: 103931-07-3
• Molecular Formula: C₇H₇O₃S*C₅₈H₁₀₄N₂O₅PSSi
• Molecular Weight: 1171.8
• Mol file: 103931-07-3.mol

Synonyms:

Chemical Property of Toluene-4-sulfonate(2-{[(E)-(2S,3S)-3-(tert-butyl-diphenyl-silanyloxy)-2-octadecanoylamino-octadec-4-enyloxy]-methoxy-thiophosphoryloxy}-ethyl)-trimethyl-ammonium;

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Toluene-4-sulfonate(2-{[(E)-(2S,3S)-3-(tert-butyl-diphenyl-silanyloxy)-2-octadecanoylamino-octadec-4-enyloxy]-methoxy-thiophosphoryloxy}-ethyl)-trimethyl-ammonium;

There total 15 articles about Toluene-4-sulfonate(2-{[(E)-(2S,3S)-3-(tert-butyl-diphenyl-silanyloxy)-2-octadecanoylamino-octadec-4-enyloxy]-methoxy-thiophosphoryloxy}-ethyl)-trimethyl-ammonium; which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2S,3R,4E)-3-O-tert-butyldiphenylsilyl-2-octadecanamido-octadec-4-ene-1,3-diol (103931-03-9) → Toluene-4-sulfonate(2-{[(E)-(2S,3R)-3-(tert-butyl-diphenyl-silanyloxy)-2-octadecanoylamino-octadec-4-enyloxy]-methoxy-thiophosphoryloxy}-ethyl)-trimethyl-ammonium; (103931-07-3,104011-31-6)

Guidance literature:

Multi-step reaction with 2 steps

1: Et₃N / tetrahydrofuran

2: 1.) tetrazole, 2.) S₈ / 1.) acetonitrile-THF, 2.) toluene

With 1H-tetrazole; sulfur; triethylamine; In tetrahydrofuran;

DOI:10.1039/c39860000329

Reference yield:

Toluene-4-sulfonate(2-{[(E)-(2S,3R)-3-(tert-butyl-diphenyl-silanyloxy)-2-octadecanoylamino-octadec-4-enyloxy]-methoxy-phosphanyloxy}-ethyl)-trimethyl-ammonium; (115523-47-2,115589-57-6) → Toluene-4-sulfonate(2-{[(E)-(2S,3R)-3-(tert-butyl-diphenyl-silanyloxy)-2-octadecanoylamino-octadec-4-enyloxy]-methoxy-thiophosphoryloxy}-ethyl)-trimethyl-ammonium; (103931-07-3,104011-31-6)

Guidance literature:

With sulfur; In benzene; Ambient temperature;

Reference yield:

Toluene-4-sulfonate(2-{[(E)-(2S,3S)-3-(tert-butyl-diphenyl-silanyloxy)-2-octadecanoylamino-octadec-4-enyloxy]-methoxy-phosphanyloxy}-ethyl)-trimethyl-ammonium; (115523-47-2,115589-57-6) → Toluene-4-sulfonate(2-{[(E)-(2S,3S)-3-(tert-butyl-diphenyl-silanyloxy)-2-octadecanoylamino-octadec-4-enyloxy]-methoxy-thiophosphoryloxy}-ethyl)-trimethyl-ammonium; (103931-07-3,104011-31-6)

Guidance literature:

With sulfur; In benzene; Ambient temperature;

upstream raw materials:

choline tosylate

Diisopropyl-phosphoramidous acid (E)-(2S,3R)-3-(tert-butyl-diphenyl-silanyloxy)-2-octadecanoylamino-octadec-4-enyl ester methyl ester

Toluene-4-sulfonate(2-{[(E)-(2S,3R)-3-(tert-butyl-diphenyl-silanyloxy)-2-octadecanoylamino-octadec-4-enyloxy]-methoxy-phosphanyloxy}-ethyl)-trimethyl-ammonium;

(2S,3R,4E)-3-O-tert-butyldiphenylsilyl-2-octadecanamido-octadec-4-ene-1,3-diol

Downstream raw materials:

C₅₇H₁₀₁N₂O₅PSSi

C₅₇H₁₀₁N₂O₅PSSi

C₅₇H₁₀₁N₂O₅PSSi

C₅₇H₁₀₁N₂O₅PSSi