4-[2-(5-hydroxypentylidene) hydrazinyl]-N-methylbenzenemethane sulfonamide

Base Information

• Chemical Name: 4-[2-(5-hydroxypentylidene) hydrazinyl]-N-methylbenzenemethane sulfonamide
• CAS No.: 151140-64-6
• Molecular Formula: C₁₃H₂₁N₃O₃S
• Molecular Weight: 299.394
• Mol file: 151140-64-6.mol

Synonyms:

Chemical Property of 4-[2-(5-hydroxypentylidene) hydrazinyl]-N-methylbenzenemethane sulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-[2-(5-hydroxypentylidene) hydrazinyl]-N-methylbenzenemethane sulfonamide

There total 4 articles about 4-[2-(5-hydroxypentylidene) hydrazinyl]-N-methylbenzenemethane sulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tetrahydro-2H-2-pyranol (694-54-2) + 4-Hydrazino-N-methylbenzenemethanesulphonamide hydrochloride (88933-16-8) → 4-[2-(5-hydroxypentylidene) hydrazinyl]-N-methylbenzenemethane sulfonamide (151140-64-6)

Guidance literature:

With sodium hydroxide; In ethanol; water; at 60 ℃; for 3h; pH 3.5;

DOI:10.1021/jo971368q

Reference yield:

3,4-dihydro-2H-pyran (110-87-2) → 4-[2-(5-hydroxypentylidene) hydrazinyl]-N-methylbenzenemethane sulfonamide (151140-64-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 63 percent

2: NaOH / ethanol; H₂O / 3 h / 60 °C / pH 3.5

With sodium hydroxide; In ethanol; water;

DOI:10.1021/jo971368q

Reference yield:

1-(4-aminophenyl)-N-methylmethanesulfonamide (109903-35-7) → 4-[2-(5-hydroxypentylidene) hydrazinyl]-N-methylbenzenemethane sulfonamide (151140-64-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) conc. HCl, 2.) NaNO₂, SnCl₂, conc. HCl / 1.) H₂O, 70 deg C, 2.) H₂O, -20 deg C, 1.5 h

2: NaOH / ethanol; H₂O / 3 h / 60 °C / pH 3.5

With hydrogenchloride; sodium hydroxide; tin(ll) chloride; sodium nitrite; In ethanol; water;

DOI:10.1021/jo971368q

upstream raw materials:

tetrahydro-2H-2-pyranol

4-Hydrazino-N-methylbenzenemethanesulphonamide hydrochloride

3,4-dihydro-2H-pyran

1-(4-aminophenyl)-N-methylmethanesulfonamide