(S_p,S_c)-3-<phosphinothioyl>-2-oxopropanoic acid

Base Information

Chemical Name:(S_p,S_c)-3-<phosphinothioyl>-2-oxopropanoic acid
CAS No.:137792-51-9
Molecular Formula:C₁₂H₁₆NO₄PS
Molecular Weight:301.303
Hs Code.:

(S<sub>p</sub>,S<sub>c</sub>)-3-<<methyl-(1-phenylethyl)amino>phosphinothioyl>-2-oxopropanoic acid

Synonyms:

Suppliers and Price of (S_p,S_c)-3-<phosphinothioyl>-2-oxopropanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S_p,S_c)-3-<phosphinothioyl>-2-oxopropanoic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S_p,S_c)-3-<phosphinothioyl>-2-oxopropanoic acid

There total 10 articles about (S_p,S_c)-3-<phosphinothioyl>-2-oxopropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 122873-88-5
(S_p,S_c)-2-(trimethylsilyl)ethyl 3-<<2-(trimethylsilyl)ethoxy>phosphinothioyl>-2-oxopropanoate

: 137792-51-9,137792-54-2
(S_p,S_c)-3-<phosphinothioyl>-2-oxopropanoic acid

Guidance literature:: With 18-crown-6 ether; cesium fluoride; In acetonitrile; at 25 ℃; for 24h;
DOI:10.1021/jo00025a031

Reference yield: 56.0%

: 122873-89-6
(R_p,S_c)-2-(trimethylsilyl)ethyl 3-<<2-(trimethylsilyl)ethoxy>phosphinothioyl>-2-oxopropanoate

: 137792-51-9,137792-54-2
(R_p,S_c)-3-<phosphinothioyl>-2-oxopropanoic acid

Guidance literature:: With 18-crown-6 ether; cesium fluoride; In acetonitrile; at 25 ℃; for 24h;
DOI:10.1021/jo00025a031

Reference yield:

: 19131-99-8
N-methyl-N-[(S)-1-phenylethyl]amine

: 137792-51-9,137792-54-2
(R_p,S_c)-3-<phosphinothioyl>-2-oxopropanoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 30 percent / n-butyllithium / tetrahydrofuran / 5 h / -78 °C

2: 41 percent / n-butyllithium, cuprous iodide / tetrahydrofuran; diethyl ether; hexane / 7 h / -30 °C

3: 56 percent / CsF, 18-crown-6 / acetonitrile / 24 h / 25 °C

With copper(l) iodide; n-butyllithium; 18-crown-6 ether; cesium fluoride; In tetrahydrofuran; diethyl ether; hexane; acetonitrile;
DOI:10.1021/jo00025a031