(2R-cis)-1--5-methyl-2,4-(1H,3H)-pyrimidinedione

Base Information

• Chemical Name: (2R-cis)-1--5-methyl-2,4-(1H,3H)-pyrimidinedione
• CAS No.: 141585-87-7
• Molecular Formula: C₁₀H₁₄N₂O₄
• Molecular Weight: 226.232
• Mol file: 141585-87-7.mol

Synonyms:

Chemical Property of (2R-cis)-1--5-methyl-2,4-(1H,3H)-pyrimidinedione

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of (2R-cis)-1--5-methyl-2,4-(1H,3H)-pyrimidinedione

There total 1 articles about (2R-cis)-1--5-methyl-2,4-(1H,3H)-pyrimidinedione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2R-trans)-tetrahydro-4-<<(4-methylphenyl)sulfonyl>oxy>-2-furanmethanol (127682-78-4) + thymin (65-71-4,28806-14-6,691841-57-3) → 1,3-Bis-((3S,5S)-5-hydroxymethyl-tetrahydro-furan-3-yl)-5-methyl-1H-pyrimidine-2,4-dione + (2R-cis)-1--5-methyl-2,4-(1H,3H)-pyrimidinedione (141585-87-7,143191-83-7)

Guidance literature:

With 18-crown-6 ether; potassium carbonate; Yield given. Multistep reaction; 1.) DMF, RT, 30 min, 2.) DMF, 80 deg C, overnight;

DOI:10.1021/jm00091a001

upstream raw materials:

(2R-trans)-tetrahydro-4-<<(4-methylphenyl)sulfonyl>oxy>-2-furanmethanol

thymin