N-(4-anilinophenyl)benzamide

Base Information

• Chemical Name: N-(4-anilinophenyl)benzamide
• CAS No.: 5249-49-0
• Molecular Formula: C₂₃H₂₆N₂O₆
• Molecular Weight: 426.469
• DSSTox Substance ID: DTXSID50350502
• Wikidata: Q82126480
• ChEMBL ID: CHEMBL1733252
• Mol file: 5249-49-0.mol

Synonyms:N-(4-anilinophenyl)benzamide;5249-49-0;Benzamide, N-[4-(phenylamino)phenyl]-;23058-58-4;N-[4-(phenylamino)phenyl]benzamide;CBMicro_020726;Oprea1_179882;Oprea1_450418;MLS001180781;SCHEMBL9479686;CHEMBL1733252;DTXSID50350502;GIXMMHJWAHQSSW-UHFFFAOYSA-N;HMS2786P11;CCG-5151;N-[4-(phenylamino)phenyl]-benzamide;STK090944;AKOS000487622;SMR000477044;BIM-0020579.P001;FT-0739483;AN-329/09302044;Z57201783

Chemical Property of N-(4-anilinophenyl)benzamide

Chemical Property:

• Vapor Pressure: 1.54E-06mmHg at 25°C
• Boiling Point: 397.9°C at 760 mmHg
• Flash Point: 133.4°C
• Density: 1.23g/cm³
• XLogP3: 4.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 288.126263138
• Heavy Atom Count: 22
• Complexity: 337

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=O)NC2=CC=C(C=C2)NC3=CC=CC=C3

Technology Process of N-(4-anilinophenyl)benzamide

There total 2 articles about N-(4-anilinophenyl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

L-glutamic acid γ-benzyl ester (1676-73-9,25014-27-1) → N-(N-Formyl-α-L-glutamyl)-D-alanin-dibenzylester (5249-49-0)

Guidance literature:

Multi-step reaction with 2 steps

1: Ac₂O

2: DCC / acetonitrile

With acetic anhydride; dicyclohexyl-carbodiimide; In acetonitrile;

Reference yield:

N-formyl-L-glutamic acid-5-benzyl ester (5249-42-3) + D-alanine benzyl ester (17831-02-6) → N-(N-Formyl-α-L-glutamyl)-D-alanin-dibenzylester (5249-49-0)

Guidance literature:

With dicyclohexyl-carbodiimide; In acetonitrile;

Reference yield:

N-(N-Formyl-α-L-glutamyl)-D-alanin-dibenzylester (5249-49-0) → N-α-L-Glutamyl-D-alanin-dibenzylester (784984-26-5)

Guidance literature:

With acetyl chloride; In benzyl alcohol;

upstream raw materials:

N-formyl-L-glutamic acid-5-benzyl ester

D-alanine benzyl ester

L-glutamic acid γ-benzyl ester

Downstream raw materials:

N-α-L-Glutamyl-D-alanin-dibenzylester