Technology Process of Benzenamine,
4-[4-(1,1-dimethylethyl)-2,6,7-trioxabicyclo[2.2.2]oct-1-yl]-
There total 14 articles about Benzenamine,
4-[4-(1,1-dimethylethyl)-2,6,7-trioxabicyclo[2.2.2]oct-1-yl]- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogen; triethylamine;
palladium on activated charcoal;
for 12h;
Ambient temperature;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 1.) methanesulfonic acid, NaNO2, 2.) aq. sodium azide / 1.) H2O, 5 deg C, 24 h, 2.) H2O, 5 deg C
2: 89 percent / KOH / methanol / 1 h / Ambient temperature
3: thionyl chloride / 5 h / Heating
4: 95 percent / pyridine / CH2Cl2 / Ambient temperature
5: 51 percent / BF3*Et2O / CH2Cl2 / 1.) -78 deg C, 1 h, 2.) RT, overnight
6: 5 mg / H2, triethylamine / 10percent Pd/C / 2 h / Ambient temperature
With
pyridine; potassium hydroxide; thionyl chloride; sodium azide; methanesulfonic acid; boron trifluoride diethyl etherate; hydrogen; triethylamine; sodium nitrite;
palladium on activated charcoal;
In
methanol; dichloromethane;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 95.5 percent / pyridine / CH2Cl2 / Ambient temperature
2: 55.6 percent / BF3*Et2O / CH2Cl2 / 1.) -78 deg C, 1 h, 2.) RT, overnight
3: 100 percent / H2, triethylamine / 10percent Pd/C / 12 h / Ambient temperature
With
pyridine; boron trifluoride diethyl etherate; hydrogen; triethylamine;
palladium on activated charcoal;
In
dichloromethane;
