6-(2,4-Dichlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde

Base Information

Chemical Name:6-(2,4-Dichlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde
CAS No.:120107-66-6
Molecular Formula:C12H6Cl2N2OS
Molecular Weight:297.16000
Hs Code.:2934100090
DSSTox Substance ID:DTXSID20401914
Wikidata:Q82205219
Mol file:120107-66-6.mol

Synonyms:6-(2,4-dichlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde;120107-66-6;6-(2,4-Dichlorophenyl)imidazo[2,1-b]thiazole-5-carbaldehyde;C12H6Cl2N2OS;DTXSID20401914;BFZJFUMQMZJNTC-UHFFFAOYSA-N;VEA10766;BBL020603;STK893292;AKOS001476236;BS-20060;CS-0335034

Suppliers and Price of 6-(2,4-Dichlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-(2,4-Dichlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde
1g
$ 330.00

TRC
6-(2,4-Dichlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde
100mg
$ 65.00

Crysdot
6-(2,4-Dichlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde 95+%
1g
$ 452.00

American Custom Chemicals Corporation
6-(2,4-DICHLOROPHENYL)IMIDAZO[2,1-B][1,3]THIAZOLE-5-CARBALDEHYDE 95.00%
5MG
$ 503.48

AK Scientific
6-(2,4-Dichlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde
250mg
$ 317.00

AK Scientific
6-(2,4-Dichlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde
100mg
$ 184.00

Total 6 raw suppliers

Chemical Property of 6-(2,4-Dichlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde

Chemical Property:

Melting Point:178-180 °C(Solv: ethanol (64-17-5))
PKA:2.89±0.40(Predicted)
PSA：62.61000
Density:1.59±0.1 g/cm3(Predicted)
LogP:4.18210
XLogP3:4.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:295.9577894
Heavy Atom Count:18
Complexity:333

Purity/Quality:

97% ^*data from raw suppliers

6-(2,4-Dichlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1Cl)Cl)C2=C(N3C=CSC3=N2)C=O

Technology Process of 6-(2,4-Dichlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde

There total 2 articles about 6-(2,4-Dichlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 120123-67-3
6-(2,4-dichlorophenyl)imidazo<2,1-b>thiazole

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 120107-66-6
5-formyl-6-(2,4-dichlorophenyl)imidazo<2,1-b>thiazole

Guidance literature:: With pyridine; trichlorophosphate; In chloroform; 1.) RT, 1 h; 2.) reflux, 9 h;
DOI:10.1016/0223-5234(88)90214-0

Reference yield:

: 4252-78-2
2,2',4'-trichloroacetophenone

: 120107-66-6
5-formyl-6-(2,4-dichlorophenyl)imidazo<2,1-b>thiazole

Guidance literature:: Multi-step reaction with 2 steps

1: 30 percent / acetone / 48 h / Heating

2: 90 percent / POCl₃, pyridine / CHCl₃ / 1.) RT, 1 h; 2.) reflux, 9 h

With pyridine; trichlorophosphate; In chloroform; acetone;
DOI:10.1016/0223-5234(88)90214-0