(2Z)-2-{1-[2-chloro-4-(3-methylpyrrolidin-1-yl)benzoyl]-4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-ylidene}-N-(pyridin-2-ylmethyl)acetamide hydrochloride

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Chemical Name:(2Z)-2-{1-[2-chloro-4-(3-methylpyrrolidin-1-yl)benzoyl]-4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-ylidene}-N-(pyridin-2-ylmethyl)acetamide hydrochloride
CAS No.:530090-81-4
Molecular Formula:C₃₀H₂₉ClF₂N₄O₂*ClH
Molecular Weight:587.497
Hs Code.:

(2Z)-2-{1-[2-chloro-4-(3-methylpyrrolidin-1-yl)benzoyl]-4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-ylidene}-N-(pyridin-2-ylmethyl)acetamide hydrochloride

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Chemical Property of (2Z)-2-{1-[2-chloro-4-(3-methylpyrrolidin-1-yl)benzoyl]-4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-ylidene}-N-(pyridin-2-ylmethyl)acetamide hydrochloride

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Technology Process of (2Z)-2-{1-[2-chloro-4-(3-methylpyrrolidin-1-yl)benzoyl]-4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-ylidene}-N-(pyridin-2-ylmethyl)acetamide hydrochloride

There total 2 articles about (2Z)-2-{1-[2-chloro-4-(3-methylpyrrolidin-1-yl)benzoyl]-4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-ylidene}-N-(pyridin-2-ylmethyl)acetamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3731-51-9
2-(Aminomethyl)pyridine

: 1092770-37-0
C₂₄H₂₃ClF₂N₂O₃

: 530090-81-4
(2Z)-2-{1-[2-chloro-4-(3-methylpyrrolidin-1-yl)benzoyl]-4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-ylidene}-N-(pyridin-2-ylmethyl)acetamide hydrochloride

Guidance literature:: 2-(Aminomethyl)pyridine; C₂₄H₂₃ClF₂N₂O₃; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20 ℃;

With hydrogenchloride; In ethyl acetate;
DOI:10.1016/j.bmc.2008.09.039