(3aS,5S,9bS)-8-Methoxy-5-methyl-7-phenyl-2-triisopropylsilanyloxy-3,3a,5,9b-tetrahydro-2H-furo[3,2-c]isochromene-6,9-diol

Base Information

• Chemical Name: (3aS,5S,9bS)-8-Methoxy-5-methyl-7-phenyl-2-triisopropylsilanyloxy-3,3a,5,9b-tetrahydro-2H-furo[3,2-c]isochromene-6,9-diol
• CAS No.: 1059606-40-4
• Molecular Formula: C₂₈H₄₀O₆Si
• Molecular Weight: 500.707
• Mol file: 1059606-40-4.mol

Synonyms:

Chemical Property of (3aS,5S,9bS)-8-Methoxy-5-methyl-7-phenyl-2-triisopropylsilanyloxy-3,3a,5,9b-tetrahydro-2H-furo[3,2-c]isochromene-6,9-diol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (3aS,5S,9bS)-8-Methoxy-5-methyl-7-phenyl-2-triisopropylsilanyloxy-3,3a,5,9b-tetrahydro-2H-furo[3,2-c]isochromene-6,9-diol

There total 1 articles about (3aS,5S,9bS)-8-Methoxy-5-methyl-7-phenyl-2-triisopropylsilanyloxy-3,3a,5,9b-tetrahydro-2H-furo[3,2-c]isochromene-6,9-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-Hydroxy-3-methoxy-4-((3aS,5S,7aS)-5-methyl-2-triisopropylsilanyloxy-3,3a,5,7a-tetrahydro-2H-furo[3,2-b]pyran-7-yl)-2-phenyl-cyclobut-2-enone (939019-36-0) → (3aS,5S,9bS)-8-Methoxy-5-methyl-7-phenyl-2-triisopropylsilanyloxy-3,3a,5,9b-tetrahydro-2H-furo[3,2-c]isochromene-6,9-diol (1059606-40-4)

Guidance literature:

In toluene; at 110 ℃;

DOI:10.1021/jo00104a004

Reference yield:

(3aS,5S,9bS)-8-Methoxy-5-methyl-7-phenyl-2-triisopropylsilanyloxy-3,3a,5,9b-tetrahydro-2H-furo[3,2-c]isochromene-6,9-diol (1059606-40-4) → (3aS,5S,9bS)-8-Methoxy-5-methyl-7-phenyl-3,3a,5,9b-tetrahydro-2H-furo[3,2-c]isochromene-2,6,9-triol

Guidance literature:

With hydrogenchloride;

DOI:10.1021/jo00104a004

Reference yield:

(3aS,5S,9bS)-8-Methoxy-5-methyl-7-phenyl-2-triisopropylsilanyloxy-3,3a,5,9b-tetrahydro-2H-furo[3,2-c]isochromene-6,9-diol (1059606-40-4) → (3aS,5S,9bS)-8-Methoxy-5-methyl-7-phenyl-3,3a,5,9b-tetrahydro-furo[3,2-c]isochromene-2,6,9-trione

Guidance literature:

Multi-step reaction with 2 steps

1: HCl

2: PCC

With hydrogenchloride; pyridinium chlorochromate;

DOI:10.1021/jo00104a004

upstream raw materials:

4-Hydroxy-3-methoxy-4-((3aS,5S,7aS)-5-methyl-2-triisopropylsilanyloxy-3,3a,5,7a-tetrahydro-2H-furo[3,2-b]pyran-7-yl)-2-phenyl-cyclobut-2-enone