nitro-(1-phenyl-4,5-dihydro-1H-imidazol-2-yl)-amine

Base Information

• Chemical Name: nitro-(1-phenyl-4,5-dihydro-1H-imidazol-2-yl)-amine
• CAS No.: 858222-03-4
• Molecular Formula: C₉H₁₀N₄O₂
• Molecular Weight: 206.204
• Mol file: 858222-03-4.mol

Synonyms:

Chemical Property of nitro-(1-phenyl-4,5-dihydro-1H-imidazol-2-yl)-amine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of nitro-(1-phenyl-4,5-dihydro-1H-imidazol-2-yl)-amine

There total 3 articles about nitro-(1-phenyl-4,5-dihydro-1H-imidazol-2-yl)-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

nitro-(1-nitroso-4,5-dihydro-1H-imidazol-2-yl)-amine (35878-49-0) + aniline (62-53-3) → nitro-(1-phenyl-4,5-dihydro-1H-imidazol-2-yl)-amine (858222-03-4)

Guidance literature:

DOI:10.1021/ja01164a093

Reference yield:

N-(2-chloro-ethyl)-N'-nitro-N''-phenyl-guanidine → nitro-(1-phenyl-4,5-dihydro-1H-imidazol-2-yl)-amine (858222-03-4)

Guidance literature:

With potassium hydroxide;

DOI:10.1139/v55-142

Reference yield:

N-nitro-N'-(2-nitroamino-ethyl)-N''-phenyl-guanidine (408327-66-2) → nitro-(1-phenyl-4,5-dihydro-1H-imidazol-2-yl)-amine (858222-03-4)

Guidance literature:

Multi-step reaction with 2 steps

1: concentrated aqueous HCl

2: methanol. KOH

With hydrogenchloride; potassium hydroxide;

DOI:10.1139/v55-142

upstream raw materials:

nitro-(1-nitroso-4,5-dihydro-1H-imidazol-2-yl)-amine

aniline

N-nitro-N'-(2-nitroamino-ethyl)-N''-phenyl-guanidine

Downstream raw materials:

1-phenylimidazolidin-2-one