(E)-4-[4-(dimethoxymethyl)phenoxy]but-2-enyl 2,3,4,6-tetra-O-acetyl-α-D-idopyranoside

Base Information

Chemical Name:(E)-4-[4-(dimethoxymethyl)phenoxy]but-2-enyl 2,3,4,6-tetra-O-acetyl-α-D-idopyranoside
CAS No.:1447755-46-5
Molecular Formula:C₂₇H₃₆O₁₃
Molecular Weight:568.575
Hs Code.:

Synonyms:

Suppliers and Price of (E)-4-[4-(dimethoxymethyl)phenoxy]but-2-enyl 2,3,4,6-tetra-O-acetyl-α-D-idopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (E)-4-[4-(dimethoxymethyl)phenoxy]but-2-enyl 2,3,4,6-tetra-O-acetyl-α-D-idopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (E)-4-[4-(dimethoxymethyl)phenoxy]but-2-enyl 2,3,4,6-tetra-O-acetyl-α-D-idopyranoside

There total 2 articles about (E)-4-[4-(dimethoxymethyl)phenoxy]but-2-enyl 2,3,4,6-tetra-O-acetyl-α-D-idopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2,3,4,6-tetra-O-acetyl-α,β-D-idopyranose

: 1447755-46-5
(E)-4-[4-(dimethoxymethyl)phenoxy]but-2-enyl 2,3,4,6-tetra-O-acetyl-α-D-idopyranoside

Guidance literature:: Multi-step reaction with 3 steps

1.1: dichloromethane / 0.5 h / Inert atmosphere; Molecular sieve

1.2: 1 h / 0 °C / Inert atmosphere; Molecular sieve

2.1: trimethylsilyl trifluoromethanesulfonate / dichloromethane / 4 h / -20 - 20 °C / Inert atmosphere

3.1: Hoveyda-Grubbs catalyst second generation / dichloromethane / 6 h / Inert atmosphere; Molecular sieve; Schlenk technique; Reflux

With Hoveyda-Grubbs catalyst second generation; trimethylsilyl trifluoromethanesulfonate; In dichloromethane;
DOI:10.1002/ejoc.201201648

Reference yield:

: 1447755-42-1
2,3,4,6-tetra-O-acetyl-α-D-idopyranosyl trichloroacetimidate

: 1447755-46-5
(E)-4-[4-(dimethoxymethyl)phenoxy]but-2-enyl 2,3,4,6-tetra-O-acetyl-α-D-idopyranoside

Guidance literature:: Multi-step reaction with 2 steps

1: trimethylsilyl trifluoromethanesulfonate / dichloromethane / 4 h / -20 - 20 °C / Inert atmosphere

2: Hoveyda-Grubbs catalyst second generation / dichloromethane / 6 h / Inert atmosphere; Molecular sieve; Schlenk technique; Reflux

With Hoveyda-Grubbs catalyst second generation; trimethylsilyl trifluoromethanesulfonate; In dichloromethane;
DOI:10.1002/ejoc.201201648

Reference yield:

: 1447755-46-5
(E)-4-[4-(dimethoxymethyl)phenoxy]but-2-enyl 2,3,4,6-tetra-O-acetyl-α-D-idopyranoside

: 1447755-39-6
4-(4-formylphenoxy)butyl-α-D-idopyranoside

Guidance literature:: Multi-step reaction with 3 steps

1: trifluoroacetic acid / tetrahydrofuran; water; dichloromethane / 1 h / Inert atmosphere

2: palladium 10% on activated carbon; diphenyl sulfite; hydrogen / ethyl acetate / 12 h / Inert atmosphere

3: sodium methylate / methanol / 6 h / 20 °C / Inert atmosphere

With diphenyl sulfite; palladium 10% on activated carbon; hydrogen; sodium methylate; trifluoroacetic acid; In tetrahydrofuran; methanol; dichloromethane; water; ethyl acetate;
DOI:10.1002/ejoc.201201648