6,7-Dimethoxy-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid ethyl ester

Base Information

Chemical Name:6,7-Dimethoxy-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid ethyl ester
CAS No.:120372-85-2
Molecular Formula:C₁₄H₁₅NO₅
Molecular Weight:277.277
Hs Code.:
DSSTox Substance ID:DTXSID50434619
Nikkaji Number:J1.568.789D
Wikidata:Q82249080
Mol file:120372-85-2.mol

Synonyms:120372-85-2;6,7-DIMETHOXY-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER;ethyl 4-hydroxy-6,7-dimethoxyquinoline-3-carboxylate;13436-14-1;Ethyl 6,7-dimethoxy-4-oxo-1,4-dihydroquinoline-3-carboxylate;Ethyl 6,7-dimethoxy-4-oxo-1H-quinoline-3-carboxylate;3-Carbethoxy-4-hydroxy-6,7-dimethoxyquinoline;SCHEMBL5291640;DTXSID50434619;LMEHZFXGGDLYMH-UHFFFAOYSA-N;HMS3451D06;4-Hydroxy-6,7-dimethoxy-quinoline-3-carboxylic acid ethyl ester;AMY27522;AKOS000655498;AKOS015966112;CCG-151417;SB69500;CS-0337726;6,7-dimethoxy-3-ethoxycarbonyl-4(1H)-quinolone;ethyl 4-hydroxy-6,7-dimethoxy-3-quinolinecarboxylate;6,7-dimethoxy-4-hydroxy-3-quinoline carboxylate ethyl ester;Ethyl6,7-dimethoxy-4-oxo-1,4-dihydroquinoline-3-carboxylate;1,4-Dihydro-6,7-dimethoxy-4-oxo-3-quinolinecarboxylic acid, ethyl ester;4-Oxo-6,7-dimethoxy-1,4-dihydroquinoline-3-carboxylic acid ethyl ester

Suppliers and Price of 6,7-Dimethoxy-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
6,7-DIMETHOXY-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER 95.00%
5MG
$ 503.72

Total 4 raw suppliers

Chemical Property of 6,7-Dimethoxy-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid ethyl ester

Chemical Property:

PSA：77.62000
LogP:1.72200
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:277.09502258
Heavy Atom Count:20
Complexity:420

Purity/Quality:

99% ^*data from raw suppliers

6,7-DIMETHOXY-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CNC2=CC(=C(C=C2C1=O)OC)OC

Technology Process of 6,7-Dimethoxy-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid ethyl ester

There total 7 articles about 6,7-Dimethoxy-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 87-13-8
diethyl 2-ethoxymethylenemalonate

: 6315-89-5
3,4-dimethoxyaniline

: 13436-14-1,120372-85-2
ethyl 6,7-dimethoxy-4-oxo-1,4-dihydro-3-quinolinecarboxylate

Guidance literature:: diethyl 2-ethoxymethylenemalonate; 3,4-dimethoxyaniline; at 120 ℃; for 1h;

In diphenylether; at 280 ℃; for 1h;
DOI:10.1016/j.bmc.2003.08.020