(all-E)-10>Retinal

Base Information

• Chemical Name: (all-E)-10>Retinal
• CAS No.: 100343-01-9
• Molecular Formula: C₂₀H₂₈O
• Molecular Weight: 294.362
• Mol file: 100343-01-9.mol

Synonyms:

Chemical Property of (all-E)-10>Retinal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (all-E)-10>Retinal

There total 15 articles about (all-E)-10>Retinal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

β,β-Di(3>methyl)acrylsaeure-methylester (100342-98-1) → (all-E)-10>Retinal (100343-01-9,100429-64-9,100483-09-8)

Guidance literature:

Multi-step reaction with 6 steps

1: 74 percent / PPS / 6 h / 80 °C

2: 31 percent / SeO₂ / dioxane; H₂O / 12 h / Heating

3: 58 percent / benzene / 1) 1 h, reflux; 2 h, room temp.

4: 33 percent / CH₃OD/NaOD/NaBH₄ / 6 h / Heating

5: diethyl ether / 0.25 h / 0 °C

6: 1) LiAlH₄, 2) MnO₂ / 1) Ether, 15 min, -78 deg C; 1 h, -40 deg C, 2) hexane, 2.5 h, 0 deg C

With manganese(IV) oxide; sodium tetrahydroborate; lithium aluminium tetrahydride; selenium(IV) oxide; deuteriated sodium hydroxide; deuteromethanol; PPS; In 1,4-dioxane; diethyl ether; water; benzene;

DOI:10.1002/jlac.198519851013

Reference yield:

β,β-Di(3>methyl)acrylsaeure-methylester (100342-98-1) → (9Z)-10>Retinal (100343-01-9,100429-64-9,100483-09-8)

Guidance literature:

Multi-step reaction with 6 steps

1: 74 percent / PPS / 6 h / 80 °C

2: 31 percent / SeO₂ / dioxane; H₂O / 12 h / Heating

3: 58 percent / benzene / 1) 1 h, reflux; 2 h, room temp.

4: 33 percent / CH₃OD/NaOD/NaBH₄ / 6 h / Heating

5: diethyl ether / 0.25 h / 0 °C

6: 1) LiAlH₄, 2) MnO₂ / 1) Ether, 15 min, -78 deg C; 1 h, -40 deg C, 2) hexane, 2.5 h, 0 deg C

With manganese(IV) oxide; sodium tetrahydroborate; lithium aluminium tetrahydride; selenium(IV) oxide; deuteriated sodium hydroxide; deuteromethanol; PPS; In 1,4-dioxane; diethyl ether; water; benzene;

DOI:10.1002/jlac.198519851013

Reference yield:

β,β-Di(3>methyl)acrylsaeure-methylester (100342-98-1) → (13Z)-10>Retinal (100343-01-9,100429-64-9,100483-09-8)

Guidance literature:

Multi-step reaction with 6 steps

1: 74 percent / PPS / 6 h / 80 °C

2: 31 percent / SeO₂ / dioxane; H₂O / 12 h / Heating

3: 58 percent / benzene / 1) 1 h, reflux; 2 h, room temp.

4: 33 percent / CH₃OD/NaOD/NaBH₄ / 6 h / Heating

5: diethyl ether / 0.25 h / 0 °C

6: 1) LiAlH₄, 2) MnO₂ / 1) Ether, 15 min, -78 deg C; 1 h, -40 deg C, 2) hexane, 2.5 h, 0 deg C

With manganese(IV) oxide; sodium tetrahydroborate; lithium aluminium tetrahydride; selenium(IV) oxide; deuteriated sodium hydroxide; deuteromethanol; PPS; In 1,4-dioxane; diethyl ether; water; benzene;

DOI:10.1002/jlac.198519851013

upstream raw materials:

β,β-Di(3>methyl)acrylsaeure-methylester

12>-4-Methyl-6-(2-methyl-1-propenyl)-2H-pyran-2-on

(13Z)-<8,10,12,14,19,19,19,20,20,20-D₁₀>Vitamin-A-Saeure

<3,5-D₂>-4-(3>methyl)-6-<<1,3-D₂>-2-3>methyl-4-(2,6,6-trimethyl-1-cyclohexenyl)-1,3-butadien>-2H-pyran-2-on

Downstream raw materials:

C₂₄H₂₇⁽²⁾H₁₀N

C₂₄H₂₇⁽²⁾H₁₀N

Refernces