Technology Process of 5-oxo-5,6-seco-cholest-3-en-6-al 6-semicarbazone
There total 5 articles about 5-oxo-5,6-seco-cholest-3-en-6-al 6-semicarbazone which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 546 mg / ozone / CH2Cl2; methanol / 1.5 h / -40 - -35 °C
2: 3.35 g / p-toluenesulfonic acid monohydrate / methanol / 4 h / -23 °C
3: 74 percent / 1,8-diazabicyclo<5.4.0>undec-7-ene (DBU) / hexane / 19 h / Ambient temperature
4: 83 percent / 7percent oxalic acid, SiO2 / CH2Cl2; H2O / 2 h / Ambient temperature
5: 21 percent / sodium acetate trihydrate / H2O
With
sodium acetate; oxalic acid; silica gel; toluene-4-sulfonic acid; ozone; 1,8-diazabicyclo[5.4.0]undec-7-ene;
In
methanol; hexane; dichloromethane; water;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 3.35 g / p-toluenesulfonic acid monohydrate / methanol / 4 h / -23 °C
2: 74 percent / 1,8-diazabicyclo<5.4.0>undec-7-ene (DBU) / hexane / 19 h / Ambient temperature
3: 83 percent / 7percent oxalic acid, SiO2 / CH2Cl2; H2O / 2 h / Ambient temperature
4: 21 percent / sodium acetate trihydrate / H2O
With
sodium acetate; oxalic acid; silica gel; toluene-4-sulfonic acid; 1,8-diazabicyclo[5.4.0]undec-7-ene;
In
methanol; hexane; dichloromethane; water;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 40 percent / hexane / 4 h / Irradiation
2: 21 percent / sodium acetate trihydrate / H2O
With
sodium acetate;
In
hexane; water;
