2-chloro-N-[4-(3-methoxyphenyl)-1,3-thiazol-2-yl]acetamide

Base Information

Chemical Name:2-chloro-N-[4-(3-methoxyphenyl)-1,3-thiazol-2-yl]acetamide
CAS No.:83558-10-5
Molecular Formula:C₁₂H₁₁ClN₂O₂S
Molecular Weight:282.751
Hs Code.:
DSSTox Substance ID:DTXSID401214529

Synonyms:83558-10-5;2-chloro-N-[4-(3-methoxyphenyl)-1,3-thiazol-2-yl]acetamide;acetamide, 2-chloro-N-[4-(3-methoxyphenyl)-2-thiazolyl]-;DTXSID401214529;MFCD03686953;AKOS003043412;2-Chloro-N-[4-(3-methoxyphenyl)-2-thiazolyl]acetamide

Suppliers and Price of 2-chloro-N-[4-(3-methoxyphenyl)-1,3-thiazol-2-yl]acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-chloro-N-[4-(3-methoxyphenyl)-1,3-thiazol-2-yl]acetamide

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:282.0229765
Heavy Atom Count:18
Complexity:293

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=CC(=C1)C2=CSC(=N2)NC(=O)CCl

Technology Process of 2-chloro-N-[4-(3-methoxyphenyl)-1,3-thiazol-2-yl]acetamide

There total 2 articles about 2-chloro-N-[4-(3-methoxyphenyl)-1,3-thiazol-2-yl]acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 586-37-8
1-(3-Methoxyphenyl)ethanone

: 83558-10-5
2-chloroacetamido-4-m-methoxyphenylthiazole

Guidance literature:: Multi-step reaction with 2 steps

1: 68 percent / I₂

2: 75 percent / benzene / 3 h / Heating

With iodine; In benzene;

Reference yield:

: 5000-65-7
2-bromo-3'-methoxyacetophenone

: 83558-10-5
2-chloroacetamido-4-m-methoxyphenylthiazole

Guidance literature:: Multi-step reaction with 2 steps

1: ethanol / Reflux

2: triethylamine / dichloromethane / 24 h / 20 °C

With triethylamine; In ethanol; dichloromethane;
DOI:10.1007/s11030-021-10310-7