(-)-2-epi-brunsvigine

Base Information

Chemical Name:(-)-2-epi-brunsvigine
CAS No.:1429046-69-4
Molecular Formula:C₁₆H₁₇NO₄
Molecular Weight:287.315
Hs Code.:

Synonyms:

Suppliers and Price of (-)-2-epi-brunsvigine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (-)-2-epi-brunsvigine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (-)-2-epi-brunsvigine

There total 12 articles about (-)-2-epi-brunsvigine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 1429055-12-8
C₁₆H₁₅NO₄

: 1429046-69-4
(-)-2-epi-brunsvigine

: 1354-81-0,1071759-60-8
(-)-brunsvigine

Guidance literature:: With diisobutylaluminium hydride; In hexane; dichloromethane; at -78 ℃; for 2h;
DOI:10.1002/anie.201307324

Reference yield:

: 1429046-70-7
C₂₂H₂₉NO₆Si

: 1429046-69-4
(-)-2-epi-brunsvigine

: 1354-81-0,1071759-60-8
(-)-brunsvigine

Guidance literature:: Multi-step reaction with 9 steps

1.1: ammonium chloride; zinc / ethyl acetate; ethanol; water / 6 h / 55 °C

2.1: tetrabutyl ammonium fluoride / dichloromethane / 0.08 h / 0 °C

2.2: 1 h / 0 °C

3.1: trifluoroacetic acid / 1,2-dichloro-ethane / 1 h / 20 - 55 °C

4.1: hydrazine; potassium hydroxide / water; ethylene glycol / 4 h / 20 - 160 °C

5.1: hydrogenchloride / water

6.1: [bis(acetoxy)iodo]benzene / methanol / 2 h / -20 °C

7.1: bis(1,5-cyclooctadiene)diiridium(I) dichloride; hydrogen / propan-1-ol / 25.5 h / 20 °C / 7600.51 - 45603.1 Torr / Inert atmosphere; Autoclave

8.1: oxalic acid / tetrahydrofuran / 5 h / 20 °C

9.1: diisobutylaluminium hydride / dichloromethane; hexane / 2 h / -78 °C

With hydrogenchloride; bis(1,5-cyclooctadiene)diiridium(I) dichloride; [bis(acetoxy)iodo]benzene; tetrabutyl ammonium fluoride; hydrogen; oxalic acid; diisobutylaluminium hydride; ammonium chloride; trifluoroacetic acid; potassium hydroxide; hydrazine; zinc; In tetrahydrofuran; methanol; propan-1-ol; ethanol; hexane; dichloromethane; water; ethylene glycol; ethyl acetate; 1,2-dichloro-ethane; 6.1: |Michael Addition;
DOI:10.1002/anie.201307324

Reference yield:

: 1429046-71-8
C₂₂H₃₁NO₄Si

: 1429046-69-4
(-)-2-epi-brunsvigine

: 1354-81-0,1071759-60-8
(-)-brunsvigine

Guidance literature:: Multi-step reaction with 8 steps

1.1: tetrabutyl ammonium fluoride / dichloromethane / 0.08 h / 0 °C

1.2: 1 h / 0 °C

2.1: trifluoroacetic acid / 1,2-dichloro-ethane / 1 h / 20 - 55 °C

3.1: hydrazine; potassium hydroxide / water; ethylene glycol / 4 h / 20 - 160 °C

4.1: hydrogenchloride / water

5.1: [bis(acetoxy)iodo]benzene / methanol / 2 h / -20 °C

6.1: bis(1,5-cyclooctadiene)diiridium(I) dichloride; hydrogen / propan-1-ol / 25.5 h / 20 °C / 7600.51 - 45603.1 Torr / Inert atmosphere; Autoclave

7.1: oxalic acid / tetrahydrofuran / 5 h / 20 °C

8.1: diisobutylaluminium hydride / dichloromethane; hexane / 2 h / -78 °C

With hydrogenchloride; bis(1,5-cyclooctadiene)diiridium(I) dichloride; [bis(acetoxy)iodo]benzene; tetrabutyl ammonium fluoride; hydrogen; oxalic acid; diisobutylaluminium hydride; trifluoroacetic acid; potassium hydroxide; hydrazine; In tetrahydrofuran; methanol; propan-1-ol; hexane; dichloromethane; water; ethylene glycol; 1,2-dichloro-ethane; 5.1: |Michael Addition;
DOI:10.1002/anie.201307324