6,6-dimethyl-2-(4-nitro-phenyl)-5-oxo-3-phenyl-heptanenitrile

Base Information

• Chemical Name: 6,6-dimethyl-2-(4-nitro-phenyl)-5-oxo-3-phenyl-heptanenitrile
• CAS No.: 857787-69-0
• Molecular Formula: C₂₁H₂₂N₂O₃
• Molecular Weight: 350.417
• Mol file: 857787-69-0.mol

Synonyms:

Chemical Property of 6,6-dimethyl-2-(4-nitro-phenyl)-5-oxo-3-phenyl-heptanenitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6,6-dimethyl-2-(4-nitro-phenyl)-5-oxo-3-phenyl-heptanenitrile

There total 1 articles about 6,6-dimethyl-2-(4-nitro-phenyl)-5-oxo-3-phenyl-heptanenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4,4-dimethyl-1-phenyl-1-penten-3-one (538-44-3) + phenylacetonitrile (140-29-4) → 6,6-dimethyl-2-(4-nitro-phenyl)-5-oxo-3-phenyl-heptanenitrile (857787-69-0)

Guidance literature:

DOI:10.1021/ja01340a032

Reference yield:

6,6-dimethyl-2-(4-nitro-phenyl)-5-oxo-3-phenyl-heptanenitrile (857787-69-0) → 6,6-dimethyl-2-(4-nitro-phenyl)-5-oxo-3-phenyl-heptanoic acid (340159-40-2)

Guidance literature:

With acid; optically inactive substances of mp: 208-215 degree;

DOI:10.1021/ja01340a032

Reference yield:

6,6-dimethyl-2-(4-nitro-phenyl)-5-oxo-3-phenyl-heptanenitrile (857787-69-0) → 6,6-dimethyl-2-(4-nitro-phenyl)-5-oxo-3-phenyl-heptanoic acid ethyl ester (340170-18-5)

Guidance literature:

Multi-step reaction with 2 steps

1: acid

2: hydrogen chloride

With hydrogenchloride;

DOI:10.1021/ja01340a032

upstream raw materials:

4,4-dimethyl-1-phenyl-1-penten-3-one

phenylacetonitrile

Downstream raw materials:

6,6-dimethyl-2-(4-nitro-phenyl)-5-oxo-3-phenyl-heptanoic acid

6,6-dimethyl-2-(4-nitro-phenyl)-5-oxo-3-phenyl-heptanoic acid ethyl ester