Phenol, 4,4'-(dimethylsilylene)bis[2,6-bis(1,1-dimethylethyl)-

Base Information

• Chemical Name: Phenol, 4,4'-(dimethylsilylene)bis[2,6-bis(1,1-dimethylethyl)-
• CAS No.: 120978-73-6
• Molecular Formula: C30H48O2Si
• Molecular Weight: 468.795
• DSSTox Substance ID: DTXSID40467456
• Wikidata: Q82294410
• Mol file: 120978-73-6.mol

Synonyms:120978-73-6;Phenol, 4,4'-(dimethylsilylene)bis[2,6-bis(1,1-dimethylethyl)-;SCHEMBL10662742;DTXSID40467456;OPMKXTSJLKQNSV-UHFFFAOYSA-N;Dimethyl-bis(3,5-di-tert-butyl-4-hydroxyphenyl)silane

Chemical Property of Phenol, 4,4'-(dimethylsilylene)bis[2,6-bis(1,1-dimethylethyl)-

Chemical Property:

• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 6
• Exact Mass: 468.34235730
• Heavy Atom Count: 33
• Complexity: 551

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)[Si](C)(C)C2=CC(=C(C(=C2)C(C)(C)C)O)C(C)(C)C

Technology Process of Phenol, 4,4'-(dimethylsilylene)bis[2,6-bis(1,1-dimethylethyl)-

There total 3 articles about Phenol, 4,4'-(dimethylsilylene)bis[2,6-bis(1,1-dimethylethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

bis(3,5-di-t-butyl-4-trimethylsilyloxyphenyl)dimethylsilane (120978-72-5) → bis(3,5-di-t-butyl-4-hydroxyphenyl)dimethylsilane (120978-73-6)

Guidance literature:

With methyllithium; In tetrahydrofuran; diethyl ether; at -30 - 20 ℃;

DOI:10.1016/j.jorganchem.2003.09.004

Reference yield:

3,5-di-tert-butyl-4-trimethylsiloxyphenyllithium (79101-69-2) → bis(3,5-di-t-butyl-4-hydroxyphenyl)dimethylsilane (120978-73-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 93 percent / diethyl ether / 20 °C

2: 55 percent / MeLi / diethyl ether; tetrahydrofuran / -30 - 20 °C

With methyllithium; In tetrahydrofuran; diethyl ether;

DOI:10.1016/j.jorganchem.2003.09.004

Reference yield:

(4-Bromo-2,6-di-tert-butylphenoxy)trimethylsilane (27329-74-4) → bis(3,5-di-t-butyl-4-hydroxyphenyl)dimethylsilane (120978-73-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 1) n-butyllithium / 1) THF, -78 deg C, hexane, 1 h; 2) THF, hexane, 24 h, RT

2: 17 percent / 1) N,N,N,N-tetra-n-butylammonium fluoride trihydrate; 2) glacial acetic acid / tetrahydrofuran / 1 h / Ambient temperature

With n-butyllithium; tetrabutyl ammonium fluoride; acetic acid; In tetrahydrofuran;

DOI:10.1016/0022-328X(89)88070-2

upstream raw materials:

bis(3,5-di-t-butyl-4-trimethylsilyloxyphenyl)dimethylsilane

3,5-di-tert-butyl-4-trimethylsiloxyphenyllithium

(4-Bromo-2,6-di-tert-butylphenoxy)trimethylsilane

Downstream raw materials:

3,5,3',5'-tetra-tert-butyl-4,4'-diphenoquinone