2-methoxy-9-(2'-dimethylaminophenyl)-9-fluorenol

Base Information

• Chemical Name: 2-methoxy-9-(2'-dimethylaminophenyl)-9-fluorenol
• CAS No.: 123519-60-8
• Molecular Formula: C₂₂H₂₁NO₂
• Molecular Weight: 331.414
• Mol file: 123519-60-8.mol

Synonyms:

Chemical Property of 2-methoxy-9-(2'-dimethylaminophenyl)-9-fluorenol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-methoxy-9-(2'-dimethylaminophenyl)-9-fluorenol

There total 1 articles about 2-methoxy-9-(2'-dimethylaminophenyl)-9-fluorenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

2-methoxy-9-fluorenone (3133-07-1) + (2-(dimethylamino)phenyl)magnesium bromide (90421-10-6) → 2-methoxy-9-(2'-dimethylaminophenyl)-9-fluorenol (123519-60-8)

Guidance literature:

In benzene; for 1h; Heating;

DOI:10.1246/bcsj.62.1093

Reference yield:

2-methoxy-9-(2'-dimethylaminophenyl)-9-fluorenol (123519-60-8) → 9-(2-Dimethylamino-phenyl)-9H-fluoren-2-ol (123519-66-4)

Guidance literature:

With phosphorus; hydrogen iodide; In acetic acid; for 3h; Heating;

DOI:10.1246/bcsj.62.1093

Reference yield:

2-methoxy-9-(2'-dimethylaminophenyl)-9-fluorenol (123519-60-8) → 2-methoxy-9-(2'-dimethylaminophenyl)fluorene

Guidance literature:

Multi-step reaction with 2 steps

1: red phosphorus, HI / acetic acid / 3 h / Heating

2: NaOH / methanol / 1 h / Heating

With phosphorus; sodium hydroxide; hydrogen iodide; In methanol; acetic acid;

DOI:10.1246/bcsj.62.1093

upstream raw materials:

2-methoxy-9-fluorenone

(2-(dimethylamino)phenyl)magnesium bromide

Downstream raw materials:

9-(2-Dimethylamino-phenyl)-9H-fluoren-2-ol

Refernces